lamictal and cbd oil

Lamictal And CBD Oil Interaction

By Jonathan Post date

Drug interactions can be life threatening. That being said it is important that you consult a doctor before taking a new medicine on a daily basis. Your doctor may or may not allow you to consume a new drug with a previously prescribed medicine due to possible chemical interactions. One of the most common drug interactions is the lamictal and CBD Oil Interaction. This article will help you understand the composition and affects of the two products individually followed by the consequences of an interplay between the two substances.

What is CBD Oil?

Cannabidiol CBD Oil is a natural medicine extracted from the cannibas plant. It is proved to have many therapeutic benefits which can help reduce the effects of anxiety, depression and many other neurological disorders including Parkinson’s. CBD serums that are medically certified contain a small amount of THC also known as tetrahydrocannabinol.THC is a psychoactive element found in cannibas that makes you feel “high”. However, since CBD Oils only contain some traces of this substance, it will not have any psychoactive affects on the user. Here’s a list of some widely known benefits of CBD Oils:

Chronic Pain and Inflammation

People who have been suffering from chronic pain as a result of fibromyalgia have experienced relief after using CBD oil. This natural medicine prevents the degeneration of the nervous system and many studies show that CBD has helped in the treatment of sclerosis and has even helped reduce cancer pain.


CBD oils have been proven to have anti-seizure properties which can successfully treat children who have been suffering from drug resistant neurological disorders like epilepsy. In June 2018, the US Food and Drug Administration approved the prescription of a purified form of CBD oil known as “Epidiolex”. This has helped treat two severe and rare forms of epilepsy found in children at the age of 2 or older. These two forms of epilepsy known as the Darvet syndrome and the Gastaut syndrome generally don’t respond to any other type of anti-seizure medications.

Anxiety and depression

In 2015, the journal Neurotherapeutics proved that CBD Oil is beneficial for people suffering from anxiety and depression. This non-psychoactive compound can help cure some anxiety related behaviors like:

  • Panic Disorder
  • Substance abuse disorder
  • Post-traumatic stress disorder (PTSD)
  • Obsessive-compulsive disorder (OCD)

What is Lamictal?

Lamictal is a drug used alone or with other medicines to prevent and control the occurrence of seizures. It is also be used to reduce mood swings or avert bipolar disorders in adults. This drug is known as antiepileptic or anticonvulsant as it works on restoring the balance of substances found in the brain.

Before using this drug you need to make sure that you are not allergic to lamotrigine. If so, immediately stop the use of lamictal as it can lead to a life threatening rash especially in children or adults who are taking a very high dose. People using this medicine might have thoughts about suicide thus, regular visits to the doctor are a must. Also, ask your friends and family to monitor the changes in your mood. Furthermore, this product can reduce the effectiveness of hormonal birth control products including pills, patch or rings.

Drug Interaction – CBD & Lamictal

Cytochrome P450 is a family of enzymes that helps oxidize fatty acids and steroids. They are also important for hormone synthesis and breakdown. These enzymes can be induced or inhibited by drugs which can result into clinically significant drug to drug interactions that can cause therapeutic failures or other unanticipated adverse reactions.

Cannabidiol can inhabit the ability of the P450 to metabolize certain drugs and in this case the metabolization of lamictal. Once the ability of P450 to metabolize is reduced, it leads to higher levels of lamictal in the blood which can lead to an overdose. An overdose of lamictal can cause troubled breathing, unusual eye movements and loss of unconsciousness. If any of this symptoms occur, take the patient to the hospital immediately as it may be life threatening.

Using CBD Oil with lamictal can result into dizziness, drowsiness and difficulty in concentrating. This is due to the reduced ability of your body to breakdown lamictal for use against the occurrence of seizures. The affects are most prominent amongst elderly people who may also suffer from impairment in thinking or accessing a certain situation. In other words, their motor coordination is severely affected so it takes them longer to understand or react to a certain situation. This means that they will need a guardian with them at all times.

Safe Use of Drugs

Before using any medicines it is important that you make an appointment with your doctor. While you may think that using two drugs at a time will help reduce the symptoms of the disease, this is not the case. Drug interactions are real and dangerous; they can lead to life threatening situations. In some cases the adverse effects of a drug interaction may not appear at first; even though your body knows that there is a drug imbalance in your body. This is more dangerous since you may not know that something is wrong before the situation becomes serious. However in other drug interactions, the adverse effects are fast and prominent. You may suffer from:

  • A Skin Rash
  • Bruising
  • Swelling
  • Dizziness
  • Severe Nausea and Vomiting
  • Diarrhea
  • Constipation

If your body shows any of the above symptoms, it is time to pay a visit to a doctor and stop the use of CBD Oils completely.

You must understand that CBD is a natural medicine and cannot be used in place of any other medicine that has been prescribed by the doctor. This is mainly because the drug has different effects on different people. It might work great for some people and may not have any benefits for others. Thus, it is foolish to depend on CBD to cure a disease. While it may suppress the symptoms, it is not an alternative to allopathic medicines.

Lamictal And CBD Oil Interaction By Jonathan Post date Drug interactions can be life threatening. That being said it is important that you consult a doctor before taking a new medicine on


“My son takes 60 mg of lamictal, two times a day. His seizures are under control, but it affects his mood. Is it safe to incorporate cbd oil with his treatment?”

Always check with your doctor BUT yes CBD would be beneficial to take as a supplement to your son’s lamictal prescription. I highly recommend looking into products like Evie’s Drops from CBD Alive or Jayden Juice CBD Tincture.

It sounds similar to your situation, and I would read the comments below the article as well. A lof of people have chimed in on this, and for many of them, their children were taking Lamictal when they introduced them to CBD.

Hopefully one of our doctors will have a chance to give you some advice as well. In the meantime, I hope this information is helpful!

Often parents do use CBD to supplement and/or wean off of traditional antiepileptics. However, dosing of the CBD can be tricky, and there are known medication interactions between CBD and AEDs, so this is definitely a journey you need to undertake with the full cooperation of your neurologist. I hope it works out well for you.

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