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Everything You Need to Know About CBD and IBS

Posted on June 11th, 2020

There’s lots of research focusing on the relation between CBD and IBS. Specifically, scientists from all corners of the world focus on understanding how CBD can be used to affect people with irritable bowel syndrome (IBS).

IBS is a poorly understood health condition, and it can seriously affect a patient’s quality of life. While we don’t know what causes IBS, we do know that some conditions, such as stress, anxiety, and inflammation are all closely linked to its symptoms. Therefore, researchers believe that addressing these factors could also help those with IBS find some relief.

And here’s the good news: findings from pre-clinical studies demonstrate that CBD may reduce inflammation, anxiety, and stress in your body. So, as research progresses, we may prove that CBD could effectively target IBS symptoms as well.

Ready to learn more? Just read on below to find out everything you need to know about CBD and IBS.

What Is IBS?

Irritable Bowel Syndrome is a chronic health condition affecting the digestive tract. IBS mostly affects your small and large intestines, and the condition triggers seemingly random episodes of discomfort and bowel pain. Millions of people, of all ages, suffer from this frustrating condition, struggling to find relief.

There are so many obstacles to treatment, the first of which is that IBS is hard to diagnose. Why? IBS sufferers generally changes how your digestive system works, whereas conditions such as Crohn’s disease cause digestive tract abnormalities. Still, symptoms often look the same, so it can take numerous visits to the doctor’s office before your IBS is properly diagnosed.

IBS Symptoms

In addition to causing random bursts of pain and discomfort along your digestive tract, IBS is also linked with a few other symptoms. These include everything from bloating, gas, cramps, constipation, and diarrhea, to abdominal pain and even weight loss. Fatigue, incontinence, and nausea may also be part of your IBS experience.

Typically, IBS is classified as being diarrhea or constipation dominant; but some patients swing from one dominance to the other. During periods of stress and anxiety, or just after eating, these symptoms usually worsen.

While there is no cure for IBS, various therapies have been developed in a bid to help relieve painful symptoms, thus improving the quality of life for IBS sufferers.

Causes of IBS

It is important to note that researchers have yet to identify the main cause of IBS. However, some medical experts believe that bacteria in the digestive system, nerves involved in the control of the digestive tract, and changes in intestinal motility resulting in food passing too slowly or too quickly through the digestive tract may be to blame.

Various foods as well as hormonal changes are also thought to trigger IBS. Individuals suffering from mental conditions, like anxiety and depression, are also more likely to suffer from irritable bowel syndrome. As previously stated, stress may cause IBS symptoms to become worse.

Traditional IBS Treatments

Over the years, medical practitioners have explored a number of treatments to treat the main symptoms of IBS.

Stress reduction therapies, such as exercise, counseling, and meditation, are commonly used to treat IBS symptoms. In most cases, medical experts start by trying to reduce anxiety and stress levels in patients.

Diet changes are another approach physicians use to treat IBS. Here, medical practitioners usually identify problematic foods, such as those known to cause digestion issues or gas, before advising patients to avoid them as much as possible.

Various medications may also be used to treat IBS. Probiotics and antibiotics may be used to alter the flora along your digestive tract. Medications that alter the intestinal motility may also be prescribed. It is also common for physicians to prescribe antidepressants to help relieve IBS symptoms. Even peppermint has been identified as an option with over the counter solutions.

While the above treatment approaches are conventional methods of addressing IBS symptoms, it is important to note their efficacy is not guaranteed; many treatments may work for some people and fail for others. Fortunately, medical experts have shifted their focus towards CBD and IBS, as they search for better treatments that effectively address the underlying IBS triggers. Plus, when the end-user says CBD helps their IBS and they convey this information to their doctor, it becomes obvious that something positive is going on in the digestive tract.

What We Know About IBS From the Latest Research Findings

Now that you have a clear idea of what IBS is, as well as its symptoms and potential causes or triggers, you can better understand how CBD can help. But you should also familiarize yourself with some of the important facts about IBS that years of research have uncovered.

First, studies show that IBS sufferers are more likely to experience inflammation along the digestive tract because they have more inflammatory cells in the digestive tract. Symptoms, such as abdominal pain and bloating, come about as inflammation sets in.

Scientists have also discovered that IBS sufferers have reduced serotonin levels. Initially, this may lead to stronger feelings of anxiety and fear, in addition to enhancing your gut’s sensitivity to pain. More importantly, serotonin in your gut influences intestinal motility, which can lead to faster movement (i.e. diarrhea,) or slower movement (i.e. constipation). When you factor in diet and lifestyle it is difficult to find a happy place with regard to IBS symptoms.

Lastly, the onset of IBS is often linked to anxiety or depression . As previously mentioned, increased stress may lead to worsening IBS symptoms. So, now we know more about IBS, let’s see why CBD is becoming popular for IBS sufferers when dealing with IBS symptoms.

What Is CBD?

We obtain Cannabidiol (CBD) from the industrial hemp plant; this cannabinoid is the main active ingredient in CBD products. Tanasi products have a patent-pending University developed formula on the extract formula that is a one-to-one concentration of CBD and the precursor, or preprocessed CBD that is Cannabidiolic-acid (CBDA). In addition to Tanasi products are all full spectrum extracts that do contain other cannabinoids, and are legal by federal guidelines.

Before you proceed, it’s important to note that CBD can not get you high, and is very different from THC (Tetrahydrocannabinol, the psychoactive ingredient in marijuana) that can get you high in larger dosage even though they both come from cannabis plants. That’s because industrial-hemp varieties of cannabis plants don’t have the THC levels that can induce a high feeling. In fact, legal CBD products usually have very low THC levels, below 0.03% in full spectrum extract form. The already-low THC levels in hemp plants are further reduced during the cannabinoid extraction and refinement process. As a result, using CBD does not come with the risk of getting high.

CBD extracts are available in a variety of delivery forms, including edibles, topicals, and concentrates, each designed to suit its use in addressing various reasons why they are consumed.

How Does CBD Work for IBS Symptoms?

While CBD has a variety of effects on the human body, it is believed to work in the following ways when it comes to IBS symptoms.

The balancing of inflammation, emotion, and pain levels in our bodies is managed, in part, by the endocannabinoid system (ECS). The ECS has been identified to regulate the organs and help synergies with the immune system. The ECS is just now being rediscovered as information about the ECS was not taught in medical schools or included in medical textbooks since the 1940s. It was a strong prohibition against the Cannabis Sativa L. plant. This system consists of receptors found all over our brains and bodies. Now, this system is important because IBS sufferers are more likely to suffer from increased mental health issues, as well as pain, and inflammation due to an endocannabinoid deficiency , according to recent research findings.

To help address inflammation, pain, and anxiety in the gut, full-spectrum CBD products also have a variety of cannabinoids and anandamide (also referred to as the “bliss molecule”) which attach to the CB1 and CB2 receptors of the ECS, which are located along the digestive tract.

CBD Dosage

To ensure that you get the best outcome when using CBD to address IBS symptoms, first consult your healthcare provider. These medical professionals can offer detailed advice on dosage and directions of use when combining CBD with other medications. The conflicts arise with anti-inflammatory drugs prescribed as taking CBD products on top of prescription anti-inflammatory is not good.

As a rule of thumb, it is recommended that you start out with a low CBD dosage level before increasing it gradually, after a few days, where necessary to achieve your desired results. Many people prefer splitting daily doses in half, one to be taken in the morning and the other before you go to sleep, at night. But others take it all in one go, so experiment with the routine that works for you. Taking over 100mg in one day is about the maximum you should take, as any more is just waste because the body can only process so much CBD.

To ensure that you have the best chance of finding the right form of CBD to address your IBS symptoms, Tanasi offers a wide selection of products. Here’s a breakdown of our patent-pending University developed hemp extract CBD products, accompanied by recommended directions for use.

  • You can take our Hemp Extract Full Spectrum Gel Capsule as desired.
  • The Hemp Extract Full Spectrum Salve is designed to be applied topically. For best results, you should not wipe the salve off your hands after a few minutes have elapsed. Just rub it in until it is no longer greasy as it is an oil-based salve.
  • Place the desired amount of the Hemp Extract Full Spectrum Oil Tincture under the tongue and only swallow after two minutes have elapsed. A desired amount might be 40mg, and that is 1mL (full dropper) of our 1200mg bottle. As an example, just take the total milligrams on the bottle, 1200mg, and divide by 30 days (1200/30 = 40).
  • Add the Water Soluble Hemp Extract Drink concentrate on your chosen drink and enjoy it. Remember to shake the concentrate well before use. The Tanasi drink concentrate products come in two sizes, 2mg per drop and 4mg per drop versions.
  • A single pump of the Hemp extract Full Spectrum Lotion should be applied over the area you desire. Our 1200mg Tanasi CBDA/CBD lotion bottle has 10mg per pump.

CBD Side Effects

CBD extract does not have many side effects that can harm you, this is why they have become federally legal. However, its use especially in higher than recommended doses might result in appetite changes, dry mouth, diarrhea, fatigue, and other mild to moderate side effects in some people. Again, taking more than 100mg per day is not recommended as it is just wasteful.

Conclusion

IBS is a common condition affecting millions of people across the globe. While a number of conventional treatments for addressing the frustrating symptoms of the condition do exist, their efficacy is limited.

Many medical experts, and patients alike, are starting to see the promise that CBD holds when it comes to addressing IBS symptoms in an easy and natural way, thanks to the mounting evidence from the many ongoing CBD and IBS studies. If you have IBS and want to try CBD as a solution to your ongoing battle with IBS we hope you choose Tanasi’s patent-pending University developed hemp extract formula of CBDA and CBD. We have identified that our formula is better than taking CBD alone.

There’s lots of research focusing on the relation between CBD and IBS. Specifically, focusing on how CBD can be used to affect people with irritable bowel syndrome (IBS).

DOES CBD HELP WITH IRRITABLE BOWEL SYNDROME

If you’ve ever wondered if CBD oil could help treat your inflammatory bowel syndrome (IBS) the answer is YES!

Irritable bowel syndrome (IBS) is the most common digestive disorder seen by physicians. It is estimated that approximately 10-15% of the population has symptoms of IBS, although fewer than half of them seek medical help for it. More than twice as many women suffer from the condition as men. (IBS is also sometimes called intestinal neurosis, mucous colitis, spastic colitis, or spastic colon, but these are outdated terms). Irritable bowel syndrome is one of a range of conditions known as functional gastrointestinal disorders. In IBS, this disorder of functioning is with the way nerves and muscles are working. In the doctor’s office nothing abnormal is seen on tests. The bowels look fine. Yet there is pain, discomfort, and other symptoms that won’t go away, or keep coming back.

In IBS, the normally rhythmic muscular contractions of the digestive tract become irregular and uncoordinated. This interferes with the normal movement of food and waste material, and leads to the accumulation of mucus and toxins in the intestine. This accumulated material sets up a partial obstruction of the digestive tract, trapping gas and stools, which in turn causes bloating, distention, and constipation.

IBS may affect the entire gastrointestinal tract, from the mouth through the colon. There are no physical signs of disease in bowel tissue with this disorder, and its cause is unknown, but one theory is that irregularities in cholecystokinin (CCK), motilin, and vasoactive intestinal peptide (VIP), are behind this disorder. According to this theory, people with IBS have abnormal contractions of the smooth muscle of the digestive tract. Some scientists believe a virus or bacterium may play a role. Lifestyle factors such as stress and diet are probably common causes, as are food allergies. The overuse of antibiotics, antacids, or laxatives, which disturb the bacterial microflora of the bowel, may also be a factor.

CBD Oil wages a war on IBS

IBS patients have struggled for many years to find a single, reliable fix. Given that IBS takes on multiple forms, and its causes are so varied, it will likely be many years (if ever) before a cure is found. However, the effects of CBD oil for IBS have been widely documented as positive.Symptoms of IBS may include abdominal pain, anorexia, bloating, constipation and/or diarrhea (often alternating), flatulence, intolerances to certain foods, mucus in the stools, and nausea.

Pain is often triggered by eating and may be relieved by a bowel movement. Because of the pain, diarrhea, nausea, and sometimes severe headaches and even vomiting, a person with IBS may dread eating. Whether or not an individual with IBS eats normally, malnutrition may result because nutrients often are not absorbed properly. As a result, people with IBS require as much as 30% more protein than normal, as well as an increased intake of minerals and trace elements, which can quickly be depleted by diarrhea.

CBD Oil Helps to regulate pain

IBS is an extremely uncomfortable condition to live with. CBD oil is known for its pain relief properties in many other medical treatments. As well as alleviating nausea, CBD oil also helps to reduce inflammation and uncomfortable swelling. Reducing these symptoms gives IBS sufferers back their daily lives, meaning that when pain flares up, they can do something about it.

Many other diseases can be related to IBS, including candidiasis, colon cancer, diabetes mellitus, gallbladder disease, malabsorption disorders, pancreatic insufficiency, ulcers and the parasitic infections amebiasis and giardiasis. More than a hundred different disorders may be linked to the systemic effects of IBS. One disorder that is linked in about 25% of adults with IBS is arthritis, usually peripheral arthritis, which affects the ankles, knees, and wrists. Less frequently, the spine is affected. IBS can also be related to skin disorders, but this is unusual. Some people with IBS have abnormalities in the levels of liver enzymes in their blood.

Diagnosis of irritable bowel syndrome requires ruling out disorders that can cause similar symptoms, such as celiac disease, colon cancer or benign tumors, Crohn’s disease, depression, diverticulitis, endometriosis, fecal impaction, food poisoning, infectious diarrhea, ischemic or ulcerative colitis, and lactose intolerance. A doctor may recommend one or more of a variety of procedures to do this, including barium enema, colonoscopy, rectal biopsy, sigmoidoscopy, and stool examination to check for the presence of bacteria, blood, and/or parasites.

Irritable bowel syndrome is painful, but not serious, and most people who have it can lead active, productive lives.

The Science about how CBD Oil Effectively Relieves the Symptoms and Treats the Cause of IBS

Even though the endo-cannabinoid system was discovered over 20 years ago, we are just starting to learn more about it and how it relates to gut health. The endo-cannabinoid system, or ECS, is a biological system found in the brain and throughout the body that includes endo-cannabinoids and cannabinoid receptors. It was the discovery of the CB1 and CB2 cannabinoid receptors back in the early 1990s that led to the establishment of the endo-cannabinoid system by Di Marzo and Fontana in 1995. The ECS is the body’s control system for maintaining homeostasis.

To understand why cannabis might be beneficial for IBS, it is useful to have a basic knowledge of the endo-cannabinoid system. The ECS helps our bodies regulate pain, mood, appetite, gastrointestinal (GI) motility, memory, emotions, stress response, immune function, and more. The ECS is a complex combination of endo-cannabinoids (cdannabinoids that out bodies naturally produce) that stimulate the body’s cannabinoid receptors, which are located in many areas of the body, such as the brain, muscles, fat, and the entire GI tract. When a person ingest THC and/or CBD, which are similar molecular shapes to endo-cannabioinds, they fit into the same receptors and trigger reactions that result in either very high or very low levels of specific molecules that the brain’s cells use to communicate with out another (neurotransmitters). This is important because a growing body of research suggests that the functioning (or lack of functioning) of the ECS has an important relationship to the pathology of IBS.

Cannabinoids can be made inside our bodies naturally and are called endocannabinoids. Cannabinoids can also be found in plants, and the most common ones come from the cannabis plant including tetrahydrocannabidioil (THC), cannabidiol (CBD) and cannabinol (CBN).Evidence suggests that dysregulation of the endo-cannabinoid system might play a role in intestinal disorders, including irritable bowel syndrome.

The fascinating thing is that our body already runs on cannabinoids. We have an entire system which runs through our body that communicates with the digestive system; the muscular system; the immune system; with the neurons in your brain – you name it – it reacts with your cannabinoid system, so you can actually use cannabis itself to “top up” your system. In terms of digestive health there is such a thing called endo-cannabinoid deficiency. This has been investigated in IBS patients; and scientific studies have found that people with IBS actually suffer an endo-cannabinoid deficiency. So using CBD oil as a treatment will allow the IBS sufferer to slowly modulate the level of gut inflammation and reduce the nasty symptoms of IBS. Strong anecdotal evidence suggests that by ingesting CBD oil and allowing it to pass through your gut, provides a layer of defence within the intestines, therefore alleviating the painful symptoms of IBS.

IBS is a functional digestive disorder that has a complex pathophysiology. Beyond the obvious digestive symptoms of gas, bloating, abdominal pain, diarrhea, and constipation lurks the altered gut motility – visceral hypersensitivity – and mood disturbances.

We do know that cannabinoid receptors are found throughout the body.
CB1 is found primarily in the brain and CB2 in the immune cells, with the majority found in the digestive system. CB1 receptors are primarily associated with memory processing, appetite, pain sensation, mood, and sleep, while CB2 receptors are involved with inflammation and pain.

For all the research on IBS and the millions of people living with this condition, medical professionals actually don’t agree on one cause behind IBS. In some cases, it can be entirely dietary. In others, it can be stress related, or a combination of the two. But while there is no decision on one reason, the symptoms of IBS are universal, and its these symptoms that cause the most trouble for people suffering from this condition.

When patients use CBD oils or extract to treat their IBS, cannabidiol interacts with cannabinoid receptors in the gut, relaxing the actual tissue there. This, in turn, leads to fewer spasmodic episodes and far less discomfort. Gastrointestinal distress with CBD oil is also reduced, further linking CBD and IBS.

As a medical condition, IBS is especially diabolical in that it affects your appetite by making you nauseated. This, in turn, prompts patients to stop eating for short periods of time, and when they get their appetite back, to over eat. As soon as they over eat, their IBS tends to flare up again. It’s a vicious cycle, and without any recourse to stop it.

In clinical studies on the link between CBD oil and IBS, the oils are shown to be effective at suppressing nausea, and promoting a healthy appetite, making it an invaluable weapon in the fight against IBS symptoms.

CBD Oil reduces Intestinal Inflammation

Gut inflammation is regulated by two important processes. The first one triggers an immune response in the gut to destroy harmful pathogens. This process, while important, can also damage the intestinal lining. This is because it causes your immune cells to attach indiscriminately, working against your body, instead of for it.
In the second process, the inflammation response is shut down via special molecules in motion across the guts epithelial. This response makes use of a naturally-produces molecule known as endo-cannabinoid.

When patients with IBS use CBD oil, endo-cannabinoids relieve gut inflammation. This is a similar effect to the use of cannabis for IBS, only with the added benefit of CBD oil being completely non-psychoactive.

CBD Oil improves Intestinal Motility

No two people experience IBS in the same way, and physical as well as mental factors come into play in a variety of combinations. Anxiety plays a large role in the expression of many IBS sufferers. Anxiety triggers over-expression of Acetylcholne in the vagus nerve. This can result from stress, and may lead to hypermotility, where food moves too quickly through the GI tract. This leads directly to IBS flair-ups and can cause loss of fluids, poor digestion and an impaired nutrient absorption.

Elevating the body’s cannabinoid intake has proved to inhibit these hypermotility states, bringing us back to CBD oil. With consistent use of CBD oil, patients increase their endo-cannabinoid levels within the gut, activating the CB1 receptor and slowing the process of food through the body, halting diarrhea.Considerations.

  • Early recognition of the disease, and drinking plenty of water, will help minimise complications.
  • It takes 12-15 hours for food to be completely processed. Meat can take longer, whereas fresh foods and raw foods are processed much more quickly.
  • Certain foods irritate the wall of the intestinal tract. Dairy products are a common culprit.
  • Avoid grains, nuts and seeds until symptoms subside.

Many people with irritable bowel syndrome have experienced improvements in symptoms after using CBD. Natural medicine has seen a massive 3% growth in Australia over the past few years, possibly due to the legalisation of medicinal marijuana in 2016. CBD oil is a burgeoning industry that is also supporting Australian’s choice to seek highly regarded preventative health and wellbeing management care. Australian’s are continuing to turn to natural therapies for their preventative health and wellbeing management with research revealing almost 70% of the population having used at least one complementary medicine in the past year.

NEWS FLASH.

In 2018, scientists at the Michigan State University identified an early cause of intestinal inflammation, one of the first stages of inflammatory bowel syndrome (IBS). The discovery points to communication between sensory neurons in the gut and a class of non-neuronal cells (enteric glia) as the culprits. In plain English… “The gut has its own brain and that has more neurons in the intestines than in the spinal cord”, said Brian Gulbransen. Within the intestines lies a ‘second brain’ called the enteric nervous system, responsible for controlling most gastrointestinal functions. Accompanying the neurons in this second brain are enteric glia, which are responsible for regulating inflammation.

Want to do more research? The entire article can be viewed in Cellular and Molecular Gastroenterology and Hepatology magazine, June 2018 issue.

DOES CBD HELP WITH IRRITABLE BOWEL SYNDROME If you’ve ever wondered if CBD oil could help treat your inflammatory bowel syndrome (IBS) the answer is YES! Irritable bowel syndrome (IBS) is the