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How long does CBD oil stay in your system?

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  1. How long does CBD oil stay in your system?
  2. How long do CBD oil effects last?
  3. Will CBD show up on a drug test?

You’ve probably heard about the therapeutic relief that cannabidiol (CBD), a non-intoxicating compound found in the cannabis plant, may offer for various conditions, from chronic pain to anxiety issues. While many people could benefit from using CBD, they may be reluctant to try it due to the fear of failing a drug test or the general stigma that still surrounds cannabis in some places.

While CBD does not produce the same intoxicating effects as THC, it does get stored in the body. Most cannabis drug tests only screen for THC, but some people may still want to know how long does CBD stay in your system?

Despite the legalization of hemp-derived CBD products in the U.S., there is still a need for further research into how CBD interacts with the body. Photo by: Gina Coleman/Weedmaps

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Despite the legalization of hemp-derived CBD products in the U.S. thanks to the 2018 Farm Bill, there is still a need for further research into how CBD interacts with the body, as well as the amount of time it remains detectable in the body after use.

However, using existing research on CBD and its interaction with the human body, we can attempt to better understand how long CBD oil stays in the system.

How long does CBD oil stay in your system?

The time that CBD remains detectable in the body will depend on several factors:

  • Metabolism: A person’s metabolism plays a prominent role in how fast the CBD is metabolized and eventually excreted from the body. Another aspect that could impact the effects of CBD is whether it’s taken with food or on an empty stomach, as certain foods could enhance bioavailability and increase overall CBD concentration in your body.
  • Frequency of Use: How often CBD is used will also influence the amount of time it remains in the body.
  • CBD Dosage: The amount of CBD taken at a time will influence how long the cannabinoid remains in the system.
  • Method of Administration: Both the effects and presence of CBD in the body are also contingent on how the cannabinoid was introduced into the body. For instance, smoking or vaping CBD allows it to take effect almost immediately, while ingestion will delay the onset for an hour or two.

In a randomized, double-blind, controlled 2005 study published in “Therapeutic Drug Monitoring,” volunteers were given cannabis extract with 2.5 milligrams of THC and 1.35 milligrams of CBD. The research team found that CBD was only detectable in the blood for up to nine hours after ingestion.

A 1991 study published in “Pharmacology Biochemistry & Behavior” examined the concentration of CBD in the blood after high doses daily. Over a six-week period, the research team administered a daily dose of 700 milligrams of CBD to 14 Huntington’s disease patients. One week after the dosing ceased, the CBD remaining in the blood was just 1.5 nanograms per milliliter and was “virtually undetectable” thereafter.

A 2018 review of existing CBD studies found that the estimated half-life of CBD was two to five days for those who took a daily oral dose. Other delivery methods delivered varied half-lifes.

While the time that CBD is detectable in the body will depend on the aforementioned factors, we can deduce that CBD will likely leave the system after a week or two. Photo by: Gina Coleman/Weedmaps

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While the time that CBD is detectable in the body will depend on the aforementioned factors, we can deduce that CBD will likely leave the system after a week or two.

That provides some insight into how long CBD remains in the blood, but there is little research on how long is CBD detectable in urine. In a 2016 study reported in the “Journal of Pain,” participants were given different types of CBD-rich cannabis products, including oils, capsules, and flower. Two hours after administration, urine samples from all 15 subjects tested positive for CBD. The researchers followed one participant after the last day of administration and found that CBD was no longer detectable in the urine after 24 hours.

It’s important to note that, while existing evidence shows us that CBD can definitely be detected in the body for a certain period of time, most cannabis drug tests specifically look for the presence of THC. Therefore, accurate information on how long CBD stays in the body remains limited compared with THC.

How long do CBD oil effects last?

Consumption method plays a crucial role in determining how long it will take to feel the effects of CBD and how long they will last.

Ingestion

Ingestion is the most common method for CBD consumption. Administering a couple of drops of CBD oil directly into the mouth is certainly a convenient way to reap the benefits of this therapeutic cannabinoid. However, ingestion is not necessarily the most effective consumption method for those who want to feel the effects of CBD immediately. Swallowing the oil prevents CBD from entering the bloodstream right away, sending it first through the digestive tract and eventually onto the liver, where it is broken down before finally reaching the bloodstream.

Studies show that when CBD compounds are metabolized by the liver, they undergo what is called the “first pass effect,” where enzymes in the liver reduce CBD concentration before the remainder is finally sent to the bloodstream and circulated throughout the body. While oral consumption of CBD has become popular for its ease of use, it’s a rather inefficient method of consumption compared with inhalation or sublingual administration. This is because only about 5% of swallowed CBD ends up in the bloodstream, meaning this method provides low bioavailability.

With ingestion, it could take anywhere from 1 to 2 hours before the effects of CBD finally set in. Photo by: Gina Coleman/Weedmaps

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Whether you’re ingesting CBD oil or CBD-infused edibles, it ultimately goes through the same lengthy digestive process and reduces the total CBD concentration in the bloodstream. With ingestion, it could take anywhere from one to two hours before the effects of CBD finally set in.

Sublingual

The sublingual method is considered to be more effective than ingestion. CBD oil can be consumed sublingually by placing a few drops under the tongue and holding it for two to four minutes, then using the tongue to rub it into the inside of the cheeks before swallowing the remainder. Using this method, CBD is transferred to the bloodstream via the mucous membranes located in the mouth, completely bypassing the digestive system and liver. Sublingual consumption leads to higher bioavailability compared to oral ingestion.

Inhalation

Inhalation is also an effective delivery method for CBD due to its rapid absorption and the efficiency of the lungs at transferring CBD into the bloodstream (better bioavailability). Whether you’re smoking a high-CBD strain or taking a draw from a CBD vape pen, the interaction with the body remains the same. When CBD is inhaled, the cannabinoids are sent directly to the lungs, where they are rapidly absorbed into the bloodstream and put into circulation.

Existing evidence suggests that CBD reaches peak blood concentration within three minutes after inhalation, meaning the effects can be felt shortly after use. Accordingly, this method is appealing for those seeking immediate pain relief.

Topical

Topical CBD comes in many forms: infused into lotions, creams, salves, and other health and wellness products. It can be applied directly to the skin where it may be absorbed through the surface of the skin and interact with localized cannabinoid receptors. In certain cases, CBD-infused topicals should be applied liberally to overcome the low cannabinoid absorption rate of the skin.

Topicals can be applied directly to the skin where it’s absorbed through the surface of the skin to interact with localized cannabinoid receptors. Photo by: Gina Coleman/Weedmaps

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Will CBD show up on a drug test?

In most cases, it’s highly unlikely that CBD oil will cause a positive test result in a drug screening. Most drug tests are developed to look specifically for the presence of THC or related substances. On top of that, employers generally abide by the Substance Abuse and Mental Health Services (SAMHSA) guidelines, which include detection for THC but not CBD.

Keep in mind that even hemp-derived CBD products are legally allowed to contain up to 0.3% THC. This could cause hesitation in some CBD-curious consumers who don’t want THC in their system or to risk a false positive result on a potential drug test. However, the chances of failing a drug test from using hemp-extracted CBD oil are extremely slim. You would need to take an exorbitant dosage of full-spectrum CBD oil (estimates range from 1,000 to 2,000 milligrams per day) to risk a positive drug test result.

For those who want to be extra-cautious and utilize CBD with no THC, a broad-spectrum oil or products that contain pure CBD isolate should do the trick. Broad-spectrum oil is refined to exclude THC, while CBD isolates contain no THC or other plant-based cannabinoids. To ensure that your CBD contains no THC, it’s important to source products from reputable manufacturers that provide a certificate of analysis from a third-party testing lab.

For those who want to be extra-cautious and utilize CBD with no THC, look for broad-spectrum oil or products that contain pure CBD isolate. Photo by: Gina Coleman/Weedmaps

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There are different types of drug tests with varying detection thresholds for THC. The most commonly used drug screening method is the urine test, which typically has a lower threshold for detection. Under the SAMHSA framework, the cutoff limit for the presence of THC is 50 nanograms per milliliter. A nanogram is one-billionth of a gram.

In the rare case that you test positive for THC after taking CBD oil, you can always try to explain the situation to your employer or request another test.

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How Long Does CBD Oil Stay In Your System?

Last Updated on 2nd November 2020

CBD Oil – How Long Does CBD Oil Take To Work?

CBD oil has been gaining popularity in recent years and has become popular among consumers in the United Kingdom. CBD is short for cannabidiol. It’s one of the cannabinoids – a family of molecules found mostly in the plant species Cannabis sativa and its subspecies and cultivars.

What Is CBD Oil?

Cannabidiol (CBD) is a component of the cannabis plant that has a wealth of proposed health benefits currently under clinical research study, being studied in many countries around the world. Since CBD oil has blown up in the media like it has, it has been an exciting time not only cannabis advocates, but for medical science.

However, how much you consume, what products you are consuming and when you consume CBD has a huge factor upon the bioavailability as well as how long the CBD will stay active in your body whether it be CBD tinctures the UK loves or vaping it in a CBD vape pen.

So, if you were wondering how long your CBD product will last for or whether you should be taking it in the morning, noon or night time to obtain the desired effects, then in this article we will guide you through the different types of CBD-laden goodies available and discuss how they will interact with your body.

How Long Does CBD Oil Stay In Your Body?

Due to the historically controversial nature of the plant from which it comes, taking CBD oil for the first time can be a concern for newcomers, especially those who undergo regular mandatory drug tests. Others are just curious as to how long the beneficial effects of CBD oil will last, and how long CBD will stay in their system.

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The effects of CBD oil are said to last from three to four hours in the human body. This means that CBD will be acting on your endocannabinoid system within this time frame. CBD oil will be interacting with the C1 and C2 cannabinoid receptors in the brain and at sites all around the body, exerting the effects it has been taken for.

The length of time that CBD oil (and almost all substances) stay in your body depends upon the initial dose of consumption and whether you engage in continued use. This is because chemicals have something called a biological elimination half-life: –

“The biological half-life of a substance is the time it takes for half of the substance to be removed via biological processes”

For CBD oil the biological elimination half-life is between 18-32 hours. So as a result, if you were to take 12mg of CBD (assuming 100% bioavailability), then it would take between 18-32 hours for that to reduce to 6mg, then the same amount of time again to reduce to 3mg, and so on. It does get a bit more complicated than this and will vary from person to person depending on factors such as metabolism.

Furthermore, just because there are still remnants of CBD floating around in your bloodstream, doesn’t mean that it is always having a strong biological effect. If you based it purely from anecdotal evidence you hear that people who consume CBD oil find that the effects start after 10-40 minutes and they will feel the effects for a further 6-24 hours depending on the dose taken, and then the effects would stop and they would require more. This is because that CBD is removed from your bloodstream as it enters different parts of your body and absorbed by the receptors of the endocannabinoid system, causing its effect.

On average, most casual users of CBD would find that it takes about 4-5 days for all traces of CBD to be removed from their system, with the biological effects stopping after 12 hours. Meaning that a dosage morning and night would suffice for it to always be biologically active.

How Long Does It Take For CBD Oil To Work?

Although it is well-known that CBD only acts on the cannabinoid receptors for three to four hours, a number of studies have been carried out to check the length of time that CBD stays in the system as a whole. Some users also wish to know the length of time that CBD will be detectable, even in trace amounts, in the human system.

One study determined that cannabidiol stays detectable in the system for three to four days. The CBD is not as biologically active at this point but if specifically tested for, it will appear in the results. CBD, as it is non-psychotropic, is not generally tested for. Using large chronic doses over a long period, another study demonstrated that the CBD stayed in the system for up to five days.

Bearing in mind, this was with extremely high doses of CBD – most practitioners will recommend around 300 mg daily, for most problems. The study illustrated used 700 mg doses daily, over six weeks, to see how the system responds to large chronic doses. It is generally accepted, therefore, that CBD will stay in the system for no more than a week, and this is at a very high dosage rate.

Does CBD Show Up On A Drugs Test and How long does CBD stay in urine?

CBD shouldn’t show up on a drugs test, however it is still possible. Why is it still possible? Many CBD products will contain trace amounts of THC, the main active ingredient in cannabis. If enough THC is present, it will be flagged on a drugs test.

The best way to avoid failing a drugs test when taking CBD oil is to use CBD products that are of both high quality and composition. Knowing what to look for when buying CBD oil can help prevent failing a drugs test.

What CBD Products Are Available?

CBD is a cannabinoid predominantly found within the buds of the cannabis plant. It is found in both marijuana and hemp, where the difference differs from country to country, however in the UK they are defined as:

  • Hemp – Cannabis which contains less than 0.2% THC.
  • Marijuana – Cannabis which contains more than 0.2% THC.

Where THC (tetrahydrocannabinol) is the psychoactive component of cannabis associated with the feelings of being ‘high’. You will find that in the UK, most CBD products will have the CBD obtained from the hemp plant to comply with the law, but this isn’t always the case around the world. So CBD and THC don’t always go together.

So, we know that CBD is in hemp buds, but this can also be extracted into oils, as well as CBD isolates, CBD gummies, CBD edibles, CBD creams, CBD balms and multiple other CBD infused cosmetic items.

Each of these different CBD based products has a different way of interacting with your body’s endocannabinoid system (ECS). For example, a CBD cream that you rub on your skin will only interact with cannabinoid receptors directly where it is applied and will provide localised relief. Whereas, a substance you ingest will have CBD enter the bloodstream where it can be transported all around the body. Even the different ways in which you can ingest CBD have different mechanisms of how they enter the bloodstream, which affects their bioavailability. This means that 10mg of CBD ingested via one method may be much more effective than 10mg of CBD ingested by another.

Find out the answers to the most common CBD oil questions. How long will it stay in your system? And will it make you fail a drugs test?