Can CBD Help With Kidney Stones?
Posted on August 25th, 2020
Kidney stones are a common, painful condition that affects many people. While you can treat kidney stones, many common therapies are invasive and painful, requiring you to stay in the hospital. Kidney specialists are always looking for new ways to prevent and treat kidney stones. And, recently, experts have explored CBD oil’s potential to address kidney stones. But first, a refresher.
If you’re suffering from kidney stones, but have never used CBD oil before, it’s a good idea to familiarize yourself with this compound and its potential benefits. So let’s take a deeper look into what CBD is and how CBD works.
What Is CBD?
Officially known as cannabidiol, CBD is a chemical compound found in the cannabis plant, both in hemp and marijuana strains. CBD comes from a larger group of naturally occurring chemicals in the cannabis plant referred to as cannabinoids.
There are somewhere between 80 and 100 different cannabinoids in the cannabis plant. Each has the potential to uniquely interact with your body. The only cannabinoid more well known than CBD is THC. This is the cannabinoid responsible for the high you experience with marijuana use.
The good news is that, if you use a hemp-extract CBD, it will only contain trace amounts of THC. This means that you can enjoy the cannabinoid’s potential benefits without the fear of intoxication.
But How Does CBD Work?
It turns out that your body produces its own internal cannabinoids. In fact, we have an entire internal system, known as the endocannabinoid system (ECS), to process internal and external cannabinoids. This complex system closely regulates many different processes in the body, including memory, food, and mood. That’s why CBD and THC produce effects in these systems and functions.
Many cannabinoids bond directly to ECS receptors, classified as CB1 and CB2 receptors. But CBD acts somewhat differently than the other cannabinoids. Instead of bonding with receptors, CBD stimulates your ECS, encouraging the production of internal cannabinoids, called endocannabinoids. It also slows the breakdown of enzymes that keep existing cannabinoids in your system.
And that’s not all: CBD affects more than 60 different pathways in your brain, influencing your serotonin reception, immune system function, and a lot more. This is why we’re constantly discovering new ways that CBD can impact our lives.
But, today, our question is: can CBD help with kidney stones? Now, there are no studies directly pertaining to this subject, but we can make an informed decision based on information from other studies. So let’s take a look at what exactly kidney stones are and how you might identify them.
What Are Kidney Stones?
Understanding the problem helps us understand how CBD oil might help. A kidney stone is actually a small concentration of minerals that collects in your urine, inside your kidney. If these minerals are not properly filtered from your urine, they form deposits or stones that are large enough to become noticeable. The most common kidney stone symptom is severe pain.
Kidney stones are most commonly formed from calcium oxalate. The calcium collects in your urine when your body doesn’t use it. The oxalate can come from vegetables, or it can be produced internally by your liver. Eating high-oxalate foods can greatly increase your risk of developing kidney stones.
Struvite stones are common if you suffer from urinary tract infections. Struvite stones can develop and grow very quickly inside your kidneys. This can result in sudden and severe symptoms.
There are two other types of kidney stones: ulric acid stones and cystine stones. Ulric stones are more common if your diet is high in fish. Cystine stones are common in patients with cystinuria. Regardless of the type of kidney stone you develop, the major symptoms are generally the same.
What Are the Symptoms of Kidney Stones?
Severe and lingering pain below your ribs in your back or side is the most common symptom. The pain can remain until you pass or surgically remove the kidney stone. Patients often struggle to find relief through pain medication. So this is one area where CBD oil may make a difference.
The pain of kidney stones may not be isolated. It can radiate into your lower abdomen and fluctuate with intensity over time. You may also experience increased pain or burning when urinating.
Many of the additional symptoms cause some level of discomfort. You may experience fever, chills, and nausea. These symptoms are more common if you have a related infection. Your urine may also be cloudy or change colors altogether. You may also feel the need to urinate frequently.
Those symptoms sound bad. And kidney stones are certainly unpleasant. So you should discuss them with your doctor, especially if the pain reaches a point of severity that limits your daily life. Fortunately, however, you may be able to address symptoms with plant-based CBD supplements.
How Can CBD Help With Kidney Stones?
One of CBD’s most well-documented properties is its ability to alleviate pain. And it appears to fight pain in different ways and from different sources. Remember, CBD stimulates the ECS and affects more than 60 different neural pathways. CBD influences the reception of pain throughout your entire body. That makes it one of the most capable potential sources of natural pain relief.
CBD’s ability to fight pain at different levels of intensity makes it a potentially valuable option for addressing kidney stones. The pain associated with kidney stones is often varied and unpredictable. You may have constant, stinging pain as well as regular flashes. CBD can help provide some level of relief for both types of pain.
CBD also has powerful anti-inflammatory properties. This is particularly useful at fighting the pain caused by kidney stones. Acute renal colic is a type of pain caused when kidney stones block the flow of urine. It is a sudden and intense pain that can be treated with anti-inflammatories. Which is why CBD oil and a bowl of blueberries may offer fast relief while you seek medical intervention.
Is CBD Oil Good for the Kidneys?
Many studies suggest that CBD oil may promote general kidney health. It’s an area that needs further research but is already showing promise. One study indicates that stimulating the CB1 and CB2 receptors improves kidney health in patients. A later study tracked the impact of CBD on patients undergoing chemotherapy. And both these studies showed that CBD oil could have an overall positive effect on kidney health and function. This suggests that CBD oil could help reduce the risk of kidney stones in the future, while also helping reduce the severity of immediate symptoms.
Is It Safe to Take CBD With Kidney Stones?
While you should talk to your doctor about your specific health conditions, CBD is considered a safe, well-tolerated supplement. It may help relieve your most severe kidney stone symptoms while promoting better kidney health going forward. If you’ve tried pain medications or other kidney stone treatments in the past without results, then it may be time to talk to your doctor about adding CBD oil to your kidney stone prevention protocol. Always look for a high-quality CBD product from a reputable source. A certificate of analysis from a third-party lab is a good indicator of a reputable source. Here, you can find the ingredients and their potency in the product.
CBD has the ability to fight pain at different levels of intensity which makes it a potentially valuable option for addressing kidney stones.
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MEDICAL MARIJUANA AND KIDNEY STONE
➡️ CBD Oil and Kidney Stones
The major work of the kidney is to remove the waste of the body like toxins, medication, and food, through the process known as the urination. Kidneys are also essential in regulating and filtering all kinds of minerals from blood before it is pumped back to the heart.
They are also responsible for maintaining fluid balance and producing the hormone, which makes red blood cell, regulate blood pressure, and improve the health of the borne. Therefore, the kidney is part of urinary tract. It consists of the ureters, urethra, and the bladder. In the kidney’s stones can form and cause a significant amount of pain and we will discuss if CBD (refers to a cannabinoid) that is found in hemp plant is good or bad for the kidneys.
The Endocannabinoid system is responsible for balancing the mood, fighting infections, immune support, and reducing the pain. When referring to kidney health, there are many conditions, disorders, and diseases, which CBD can be of great importance.
➡️ Can CBD Oil Help with Kidney Stones?
There is a study , https://www.ncbi.nlm.nih.gov/pubmed/28747360, that is studying if CBD is good at preventing kidney stones and if the oil is good or bad for the kidneys. In the study they did find that it matters as to when you apply the oil and they did have better results if the oil is applied sooner than later. There is still a lot more to study before we learn exactly what CBD can prevent and help for our kidneys.
“Experimental studies suggest that stimulation of these receptors using pharmacologic agents or their naturally occurring ligands could have both deleterious and beneficial effects on the kidneys, depending on receptor distribution, type of renal insult, or the timing of the activation during acute or chronic states of kidney injury. “
➡️ Effects of CBD
The CBDOil in Hemp,blocks inflammatory cytokines, cleanses the digestive tract, and reduces the effects of toxicity in the kidneys.
Firstly, this slows degeneration of the kidneys in those suffering from chronic kidney failure.
➡️ What Are Kidney Stones?
Kidney stones refer to solid masses that are crystal minerals and substances from the blood, which structure in the kidneys. Generally, they are passed through a contraction and urination process. Typically, the process is very painful.
The stones later find their way through the urinary tract before they come out. CBD can help in pain relief with kidney stones and kidney stone pain since it uses the same pathways. Since it is a strong anti-inflammatory, the substances will help in reducing swelling in the urinary tract caused by passing the stones. Learn more about CBD and kidney stones below.
➡️ How Are Kidney Stones Formed?
Kidney stones have many causes and can affect any part of your urinary tract from your kidneys to your bladder. Often, stones form when the urine becomes concentrated, allowing minerals to crystallize and stick together.
Signs and Symptoms
• Severe pain in the side and back, below the ribs.
• Pain that radiates to the lower abdomen and groin.
• Pain that comes in waves and fluctuates in intensity.
• Pain on urination.
• Urgent need to urinate.
• Only Urinating a small amount each time.
• Pink, red or brown urine.
• Cloudy or smelly urine.
• Nausea and vomiting.
➡️ What Helps to Dissolve the stone?
You want to make sure you are staying hydrated and that means you are drinking enough water each day. Water can help flush out and stick to your 8 glasses of water a day to help keep your system moving. You can add items to your water to try and help with the flush some people swear by adding lemon to their water, apple cider vinegar and more. Basil juice has been known to help with the flush and also help with some of the pain. It takes a lot of basil so this isn’t anything that I have tried.
Be sure and speak with your Doctor before trying any of these methods as each person is different. Some of the most popular herbs we eat in our typical diets that can help are the following:
• Celery Juice or Seeds
• Kidney Bean Broth due to the higher levels of magnesium that is used to help break down.
• Extra Virgin Olive oil is a think oil that can help with the process of the stone moving through the urinary track.
Most smaller stones can be passed with out invasive treatment but your doctor will be able to tell you the actual size and if it is possible for you to pass. If you are able to pass the stone pain management and helping your body flush it out is the next best steps.
➡️ Infections in the Urinary Tract
Infections in the urinary tract should be treated to avoid spreading to the rest of the kidney. This can result in kidney failure. However, women stand at the high risk of getting the infections.
Nevertheless, many people do not recognize they have urinary tract infections or maybe mistake it for another thing.
Generally, CBD is anti-microbial and can fight bacterial, viral infections, and fungal. Cannabidiol also boosts the immune system.
➡️ Chronic Kidney
The chronic kidney disease is a condition mostly caused by diabetes and high blood pressure. Glomeruli and destroyed by the high blood pressure. Naturally, it decreases in the ability to filter the blood and function.
Typically, CBD is responsible for lowering the blood pressure that protects all the blood vessels. It also removes anxiety and stress, increasing the calmness to the user. The high presence of uncontrolled blood sugar in diabetic, also contribute to kidney failure.
➡️ Holistic Remedies for Kidney stones
Typically, kidney stones are responsible for severe pain on your back and might radiate around the groin part.
However, below are some of the natural remedies, which might be of help to you.
• Drink lot of fluids. Water, fruit juices, lemonade, can dilute any substance present in urine, which might form the kidney stones. You should avoid grapefruit and soft drinks.
• Avoid a lot of animal protein. Meals with a high level of animal proteins might lead to increased calcium within the urine. This causes oxalate stones.
• Avoid the foods that have organic acids. They help in stones formation. You should limit spinach, beetroots greens, chocolates, bran, nuts, peanuts, almonds, and strawberries. They also increase the level of oxalate.
• Use vitamin B6 and magnesium; when you take 50mg daily of vitamin B6 with magnesium, it may limit the formation of oxalate stones.
Foods to Avoid to help prevent Kidney Stones
• Cut back on your Salt Intake
• Limit Eating out as most are higher in Salt
• Limit Antacids that contain Calcium
• Try eating more lemons and oranges for the citrus
➡️ Can CBD (hemp oil) help with Kidneys Stones and Stone Pain?
Another way, in which CBD may help people against kidney pain, is by offering an option above traditional medicines that are used as the painkillers and treat other conditions. Typically, the chemical consumption found in the medicines are also very harmful to the kidney otherwise known as side effects. Sometimes holistic and natural remedies do offer a better option but you must be the one to decide the best route for your health.
Therefore, drugs could contribute a lot to kidney damage if not careful. When these chemicals get into the bloodstream, they provide an overload to the kidney. It is very important to take drugs under the prescription of the doctor. Be sure to ask your doctor all of the side effects before taking any medications.
Legalise it for medicinal purpose.
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The Ganja Guru
MEDICAL MARIJUANA AND THYROID CANCER.
Approximately 39.6% of people will receive a cancer diagnosis at some point in their lifetime. The disease disrupts and takes the lives of people who have it and also significantly impacts the people that care about them. Unfortunately, we don’t have a definite cure so, currently, the best we can do is manage cancer symptoms and give it our all with the treatment solutions we have.
An important step in the fight against cancer is learning all you can about the disease. The more we know about cancer, often the easier it is to treat it. That knowledge includes alternative treatments like medical marijuana.
➡️ What Does the Thyroid Do?
Most people understand what commonly known organs like the stomach and lungs do. But what about the thyroid?
The thyroid is a butterfly-shaped gland that moderates hormones that control metabolism and calcium use. Its follicular cells make thyroid hormones that normalize metabolism to maintain the way that the body uses calcium, the thyroid’s C cells create a hormone called calcitonin.
➡️ Butterfly shaped gland thyroid cancer.
When you have an abnormal number of thyroid hormones, you experience health problems related to your metabolism. Hypothyroidism occurs when you have too few thyroid hormones, making you feel tired and slow. If you have a high number of thyroid hormones, you have hyperthyroidism, which quickens your heartbeat and makes you feel on-edge.
➡️ About Thyroid Cancer.
A healthy body regularly creates new cells to replace old ones. Usually, the old cells die off to make room for the new cells. But, when you have cancer, your old cells don’t die off, causing health problems and even death.
We name a cancer after the place in the body it starts in, so thyroid cancer is cancer that begins in the thyroid. Even if the cancer eventually spreads to other parts of the body, we still call it thyroid cancer.
The three main types of thyroid cancer are:
# Differentiated thyroid cancer: Differentiated thyroid cancers include papillary cancer, follicular cancer and Hurthle cell cancer. They begin in the follicular cells in your thyroid and are the most common form of thyroid cancer.
# Medullary thyroid cancer: Medullary thyroid cancer (MTC) can be sporadic or familial, and they start in the thyroid’s C cells.Sporadic MTC is not inherited from relatives, while familial MTC is.
# Anaplastic / # undifferentiated thyroid cancer:Anaplastic thyroid cancer often develops from a papillary or follicular cancer. Doctors have the hardest time treating this type of thyroid cancer.
Medical Marijuana and Thyroid Cancer
➡️ Symptoms and Signs of Thyroid Cancer.
When you have thyroid cancer, you exhibit any or all of these symptoms:
•Swelling in the neck
•Pain that you feel on the front side of your neck
•Issues breathing and swallowing
•A lump in the neck
•A persistent cough and/or change in voice
Also, thyroid cancer patients deal with symptoms universal to cancer, such as:
•Severe nausea and vomiting
•Unexplained and sudden weight loss
➡️ Facts About Thyroid Cancer.
Almost every type of thyroid cancer has a nearly 100% five-year survival rate when caught in an early stage and about a 50% five-year survival rate when detected in the final stage.
Anaplastic thyroid cancer is the exception to the former It always appears in the final stage and has about a 7% five-year survival rate.
Nearly three-quarters of thyroid cancer cases are discovered in women.Women have the highest risk of getting thyroid cancer in their 40s or 50s, while men have the highest risk during their 60s or 70s.
We don’t understand why thyroid cancer affects women more frequently than men.
➡️ Diagnosing Thyroid Cancer.
Since thyroid cancer often manifests as a lump in the neck, it’s often detected early. Most cancer patients have a higher chance of survival when they get an early diagnosis. So, the high chance of early detection helps many thyroid cancer patients receive successful treatment.
Most of the time, doctors find thyroid cancer either when a patient reports neck swelling or during a regular checkup. A simple neck examination usually does the trick. In other cases, thyroid cancer can be found during an ultrasound or blood test.
➡️ Treatments for thyroid cancer.
[ How We Typically Treat Thyroid Cancer ]..
We have a few options for treating cancer. The treatment a patient gets depends on the stage of the disease, the patient’s other health problems and the patient’s personal preferences. Some of the most common thyroid cancer treatments include:
# Surgery : Surgical removal of the thyroid cancer tumor is one of the most common options. Depending on how far the cancer has progressed, the surgeon may remove all or part of the thyroid. In some cases, a patient will have to take thyroid hormones after
surgery to replace the ones that the thyroid would naturally produce.
# Chemotherapy : Chemotherapy involves dosing the patient with anti-cancer drugs intravenously or with a pill. We don’t often use chemotherapy on thyroid cancer patients since the risks usually outweigh the benefits. However, sometimes we use it for anaplastic thyroid cancer and other advanced forms.
# Targeted # therapy : The medical world has begun to develop drugs that target certain kinds of cancer cells. Unlike chemotherapy, it doesn’t kill off any rapidly growing cell, so targeted therapy drugs are more efficient than chemotherapy drugs when used correctly.
# Radioactive # iodineTherapy : Some doctors use the thyroid’s tendency to absorb iodine to their advantage. To send radiation directly to the thyroid, the physician gives the patient radioactive iodine that kills only iodine-absorbing cells. Unfortunately, the radioactive iodine doesn’t differentiate between healthy cells and cancer cells.
# Hormone therapy: If the thyroid cancer appears outside of iodine-absorbing cells, doctors can also use external beam radiation therapy. Instead of receiving radiation internally as you would with radioactive iodine, a physician administers a radioactive beam outside the body.
Many of these treatments take a substantial toll on your body, so you and your doctor must take care when choosing one.
➡️ Medicating with Medical Cannabis for Thyroid Cancer.
Medical marijuana is unique because it can address multiple health problems at once without severe side effects for most patients. Thanks to its versatile nature, cancer patients can pick a strain to suit the symptoms they experience, including cancer symptoms. In fact, medical cannabis almost seems tailor-made for cancer relief — many of the symptoms it commonly relieves appear in cancer patients, including:
• Pain: Cancer and its treatments often cause chronic and severe pain. Fortunately, most states with a medical marijuana program have pain at the top of their list of conditions that qualify for the drug. This is because we have done tons of research on pain and marijuana.
• Nausea/Appetite Loss: Many cancer patients have a difficult time eating either due to nausea or loss of appetite. It doesn’t help that thyroid cancer patients must deal with difficulty swallowing and inflammation in their throat. Marijuana can boost your appetite and relieve nausea.
• Fatigue: Depending on the strain you pick, you can get a burst of energy from using marijuana. A sativa strain can help you manage the brain fog and fatigue associated with cancer and cancer treatments.
• Insomnia: Alternatively, indica marijuana strains have sedative properties. When the other symptoms of thyroid cancer keep you up at night, you can use your weed to sleep better.
In addition to addressing symptoms caused by thyroid cancer, research suggests that it could tackle the disease itself.
Researchers have been considering marijuana’s potential for killing and reducing the spread of cancer cells. While we don’t know if it can ultimately cure cancer, studies indicate that it could help teach us what a successful cancer treatment looks like. When you add that to its ability to help patients with other cancer symptoms, you get a great supplement to cancer treatment.
However, when we deal with organs related to hormones, we should take care when using cannabinoidslike THC.A study on men suggested that THC can reduce thyroid hormones, which isn’t ideal for patients with thyroid cancer. Since the study only used male subjects, we have much more research to do to understand the whole situation.
➡️ Thyroid Cancer & Medical Marijuana Research
Thyroid cancer is the most common malady affecting the endocrine system, and it’s also the deadliest. Three types of thyroid carcinomas can occur in patients:
Although the first two have a fairly good prognosis for patients, the latter, anaplastic, is highly aggressive. A 2008 research study performed by the Department of Genetics at King Faisal Specialist Hospital and Research Center in Saudi Arabia explored the possibilities of using cannabis in cancer gene therapy.
In their report entitled “Cannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma,” researchers found that using marijuana to induct the endocannabinoid receptor CB2 allowed for cancer gene therapy to have a more profound effect.
They also learned that when combined with cancer-fighting gene therapy, the induction of CB2 receptors contributed to thyroid tumor regression and prevented the growth of anaplastic tumors by:
Allowing the immune system to function and respond to the tumor
Preventing the formation of new blood vessels that enable tumor nutrition.
➡️ How to Take Medical Marijuana for Thyroid Cancer ?
You have way more options for marijuana use than just smoking. Both the medical and recreational marijuana industries have worked hard to make their products usable for everyone. Certain methods will work better than others for thyroid cancer. Let’s see how they compare:
# Smoking : As a way to inhale cannabis, smoking provides fast relief when you need your medicine right away. But, like tobacco smoke, weed smoke contains dangerous toxins that damage your respiratory system. For optimum health benefits, you may want to pass on smoking marijuana.
# Vaping : On the other hand, vaping has the immediacy of smoking without being as unhealthy. If you pick a vaporizer that doesn’t scorch your marijuana, you can avoid inhaling any smoke byproducts.
# Edibles : Edible marijuana products may do the job for you but only in certain cases. They aren’t ideal for patients having difficulty swallowing due to a thyroid tumor or patients experiencing nausea. Also, the effects of edibles are slow and more unpredictable.
# Topicals : Depending on how much your tumor presses on the outside, topicals can work decently or not at all. Patients usually use lotions and creams for muscles aches and other local pain. But a patch can transfer cannabinoids right to your blood and travel to your thyroid.
# Pills and # tinctures : Some medical marijuana products closely resemble the medicine you would get at a pharmacy. You can take Cannabinoid capsules like a typical pill, and place tinctures under the tongue to be absorbed into the skin there.
# Oils : # CBD oil is isolated cannabidiol (CBD) in oil form. You can vape CBD oil or add it to a meal.
Picking the right cannabis medicine can prove very difficult, especially if you haven’t used marijuana before. When in doubt, check in with your doctor or dispensary. They can provide guidance based on your personal needs.
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The Ganja Guru
MEDICAL MARIJUANA CBD FOR KIDNEY FAILURE (LATEST RESEARCH NOVEMBER 2020)
Can CBD help with kidney disease, and if so, how?
Kidney failure, also called renal failure or end-stage renal disease, is the last stage of chronic kidney disease.
When the kidneys fail, it means they have stopped working well enough for the person to survive without dialysis or a kidney transplant.
However, even these remedies are not without adverse side effects. For instance, researchers found an increased incidence of kidney stones in patients after a kidney transplant.
Calcium based stones, such as calcium oxalate and calcium phosphate, were the most common types of kidney stones found after kidney transplantation.
Meanwhile, studies have examined the use of nonsteroidal anti-inflammatory drugs (NSAIDs) for chronic kidney disease (CKD).
Findings suggested that short-term NSAID use has adverse side effects on blood pressure elevation.
High blood pressure is the second principal cause of kidney failure in the United States after diabetes.
CBD for Kidney Disease: What the Research Says ?
There are no studies specific to the use of CBD alone and its impact on kidney health. There are, however, limited studies that examined the effects of cannabis on kidneys, and they produced mixed results.
During the American Society of Nephrology’s Kidney Week conference in October 2018, researchers shared their findings from a recent study on medical marijuana use and its side effects on kidneys.
Marijuana and hemp belong to the same plant species, Cannabis sativa, but are widely different. Marijuana contains much more tetrahydrocannabinol (THC) than hemp, while hemp contains more cannabidiol (CBD).
The researchers, who studied kidney disease progression in cannabis users, found that chronic kidney disease (CKD) patients’ kidney function declined faster in those who used cannabis, compared to those who did not.They did not report whether this was marijuana or hemp-derived cannabis which would have lower THC than CBD.
Joshua L. Rein, DO, who led the study, warned that kidney patients using cannabis should be aware of potential symptoms, such as nausea, lack of appetite, and chronic pain, which are all valid issues for medical marijuana usage. Meanwhile, researchers of a study published in the Journal of Pain and Symptom Management believe that even minor improvements in patients with difficult-to-treat CKD symptoms may be clinically meaningful. In their research, they found that cannabinoids, like CBD and THC, may present a reasonable alternative to pain and symptom management.
Another study, which was published in the Journal of Pharmacology and Experimental Therapeutics, showed that CBD might help reduce nephrotoxicity by decreasing oxidative stress, inflammation, and cell death.
Nephrotoxicity occurs when the body is exposed to a drug or toxin that causes kidney damage, which makes the body unable to eliminate excess urine and wastes.
Still, due to limited treatment options for chronic kidney disease (CKD), symptom management can be challenging. Thus, therapeutic alternatives are in high demand, which may explain why, in recent years, medical marijuana has emerged as an attractive therapeutic option.
As a result, medical cannabis continues to be used for a variety of indications with minimal guidance on known risks, particularly on the altered physiological state of patients with chronic kidney disease (CKD).
How CBD Works: The Endocannabinoid System Explained
According to a study published in the American Journal of Physiology – Renal Physiology in 2017, the endocannabinoid system (ECS) plays a crucial role in renal homeostasis.
While data suggest cannabis and cannabinoids could have essential effects on kidney function, there is not sufficient evidence from clinical research studies to determine the dangers faced by users of these products with respect to the development of acute kidney injury (AKI) or CKD.
A 2016 review looked into the emerging role of the endocannabinoid system, particularly the cannabinoids and the cannabinoid receptors, in normal kidney function and other diseases, such as diabetes and obesity, that directly contribute to the development of renal diseases.
The authors of the said review found that the activation of the CB1 receptor regulates renal vascular blood flow. Meanwhile, the renal CB2 receptor reduces the effects of inflammation, oxidative stress, and renal fibrosis.
Types of Dialysis / Kidney Disease and Side Effects
There are two types of dialysis:
•Hemodialysis : when an artificial kidney called a hemodialyzer removes waste and chemicals from the blood.
•Peritoneal : which is performed by surgery with catheters to cleans the blood from inside the body.
How Cannabinoids Might Influence Dialysis / Kidney Disease ?
CKD and dialysis inevitably affect blood pressure, which has proven to be regulated by medical cannabis. A 2012 U.S. National Health and Nutrition Examination Survey reported that preclinical studies demonstrated a dose-dependent increase in blood pressure with cannabis. Good or bad, the pressure change from cannabis concludes that its properties can regulate compression. CKD also causes problems sleeping, making insomnia an unwelcome side effect of dialysis. Again, medical cannabis proves to help the symptom by the non-psychoactive cannabidiol CBD and psychoactive THC.
As far back as 2008, long before medical cannabis was highly considered, a study reported by journal Sleep Medicine Reviews showed how “smoked marijuana and oral Delta-9-tetrahydrocannabinol (THC) reduce REM sleep. Moreover, acute administration of cannabis appears to facilitate falling asleep and to increase Stage 4 sleep.”
Pericarditis, a prevalent symptom of CKD and dialysis, causes abnormal inflammation, one of the most popular conditions treated with medical cannabis. One of the most popular reports proving that CBD is good for inflammation was published in a 2009 edition of Future Medicinal Chemistry.
“Cannabinoid receptors include CB1, which is predominantly expressed in the brain, and CB2, which is primarily found on the cells of the immune system,” according to the study. “The fact that both CB1 and CB2 receptors have been found on immune cells suggests that cannabinoids play an important role in the regulation of the immune system.” Since inflammation is the body’s response to harm and injury, it would make sense that medical cannabis treats the condition and side effects of CKD and dialysis.
The limited treatment options among individuals with CKD increase the demand for therapeutic alternatives.
Despite the current lack of approved CBD or cannabis therapy, some patients may still want to start experimenting with medical cannabis for symptom management. However, although CBD has been used in many therapeutic applications, the evidence of its efficacy with chronic kidney disease has not been well-reviewed. Also, there is not enough literature accumulated to advise appropriately on consumption forms and dosage.
Before using CBD to treat CKD symptoms or as supplementary therapy, a consultation with a nephrologist experienced in cannabis use is strictly advised.
The more medicated. The more dedicated
The Ganja Guru
MEDICAL MARIJUANA AND ANXIETY [LATEST STUDY]
HOW TO FIGHT DEPRESSION AND ANXIETY WITH MEDICAL MARIJUANA ?
Anxiety and depression are closely related. If you have anxiety, then the chances are high that you are depressed, and the reverse is also true. Coping with these disorders is not easy. They reveal symptoms like racing thoughts, pain, reduced energy, anger, loss of appetite, and more. All of these can affect your work and relationships in different ways. They can get worse when left untreated.
You may be wondering what cannabis has to do with fighting depression and anxiety. Well, cannabis use for these conditions dates back to several years. Fast forward to today, many scientific studies now suggest that cannabis can help. Even better, CBD, a compound of cannabis, can treat these mental issues and has no psychoactive effects.
WHAT DOES RESEARCH ON CANNABIS AND CBD SAY?
Studies reveal that growing trusted marijuana seeds in US indoors as a treatment for numerous health problems like anxiety and depression is increasing. The preclinical studies show its potential in managing these conditions. The research also suggests that CBD and THC enhance the endocannabinoid system, which regulates most body functions.
So, can cannabis and CBD improve the symptoms of anxiety and depression? Let’s look at how they can help.
HOW MEDICAL CANNABIS AND CBD HELP IN TREATING DEPRESSION AND ANXIETY
Sleep problems are common issues with depression and anxiety. However, the relationship between the two is a little complex. While the lack of sufficient sleep can trigger these conditions, depression and anxiety can also disrupt sleep patterns.
High-quality medical cannabis from reputed cannabis online Canada dispensaries can help fight insomnia and other sleep problems. Its use as a sleep aid goes back thousands of years. Much of the sleep-inducing effects is owed to cannabis’s sedative and relaxing effects. Generally, marijuana allows you to fall asleep faster.
This feature was revealed in a study that concluded that cannabis reduces the time it takes to fall asleep. The participants in the study included people with sleep issues and those without them. As a result, those with sleep issues showed an improvement in falling asleep by up to 30 minutes and an average of 15 minutes for those with no sleep problems.
This study agrees with other research suggesting that cannabis reduces the time needed to fall asleep, decreases REM sleep, and increases slow-wave sleep. These effects are associated with cannabis’ THC compound.
However, cannabis works in different ways to provide better sleep and ease conditions like anxiety and depression. That’s because of the different effects caused by THC and CBD.
A study found that taking cannabis strains with high levels of THC is more effective in reducing REM sleep. It helps decrease dreams and nightmares, especially in PTSD patients.
Other research shows that CBD vape juice to help you sleep and ease anxiety. In fact, researchers investigated the effects of taking CBD daily on two groups with poor sleep and anxiety. They found a reduction of anxiety levels by 79.2 percent and improved sleep by 66.7 percent.
TREATS CHRONIC STRESS
Prolonged stressful situations can lead to depression and worsen anxiety. Researchers have looked into the role of stressful life events in the development of depression, and the findings support this claim.
New research by the University of Buffalo discovered that the endocannabinoid chemicals in the brain work the same way as the cannabinoids found in cannabis. The effect of the interaction results in an improved mood, which can ease depression and anxiety.
The experiments on rats revealed that the brain produces fewer endocannabinoids when you’re suffering from chronic stress. Introducing cannabinoids from cannabis helps restore the normal levels of endocannabinoids and consequently fight the symptoms of depression.
CBD is also becoming the go-to treatment for chronic stress. It works by reducing your body’s sensitivity to stress and possibly eliminating the severe effects of anxiety and depression. CBD does this in different ways:
CBD Promotes Brain function
As you get nervous, the sensitivity of the hypothalamus to cortisol drops. That means you need higher cortisol levels to get normal responses, and lack of it prolongs stress. CBD improves the hypothalamus’ sensitivity to cortisol, thus helping to stop stress immediately.
Protects your Body from Destruction by Stress
Stress causes damage to your body through oxidative stress. It’s a condition that leads to the accumulation of free radicals causing damage to the body and reduces its detoxification ability. CBD is a powerful antioxidant. Introducing it to the body helps counter the free radicals, thus protecting your body from damage.
CBD for Rest & Digest
When the body detects a problem, it increases the release of hormones such as cortisol and norepinephrine in the brain. These prepare the body to fight off stressful situations by increasing brain activity. But there’s a challenge caused by the opposing effects of gamma-aminobutyric acid (GABA) hormones that reduce and inhibit the activity of neurons and nerve cells.
In one study, researchers introduced cannabidiols that blocked GABA in animals. This triggered them to experience hyperactive seizures. The research concluded that CBD effectively inhibited GABA effects and can be used to ease anxiety by increasing relaxation.
Another study also shows that CBD can help ease anxiety in patients with a generalized social anxiety disorder (SAD). This condition is a common form of anxiety that impacts one’s social life. The study revealed that CBD helped ease the state and altered the brain’s response to this anxiety.
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