Categories
BLOG

cbd oil and blood pressure

7 Benefits and Uses of CBD Oil (Plus Side Effects)

Cannabidiol is a popular natural remedy used for many common ailments.

Better known as CBD, it is one of over 100 chemical compounds known as cannabinoids found in the cannabis or marijuana plant, Cannabis sativa ( 1 ).

Tetrahydrocannabinol (THC) is the main psychoactive cannabinoid found in cannabis, and causes the sensation of getting “high” that’s often associated with marijuana. However, unlike THC, CBD is not psychoactive.

This quality makes CBD an appealing option for those who are looking for relief from pain and other symptoms without the mind-altering effects of marijuana or certain pharmaceutical drugs.

CBD oil is made by extracting CBD from the cannabis plant, then diluting it with a carrier oil like coconut or hemp seed oil.

It’s gaining momentum in the health and wellness world, with some scientific studies confirming it may ease symptoms of ailments like chronic pain and anxiety.

Here are seven health benefits of CBD oil that are backed by scientific evidence.

Marijuana has been used to treat pain as far back as 2900 B.C. ( 2 ).

More recently, scientists have discovered that certain components of marijuana, including CBD, are responsible for its pain-relieving effects.

The human body contains a specialized system called the endocannabinoid system (ECS), which is involved in regulating a variety of functions including sleep, appetite, pain and immune system response ( 3 ).

The body produces endocannabinoids, which are neurotransmitters that bind to cannabinoid receptors in your nervous system.

Studies have shown that CBD may help reduce chronic pain by impacting endocannabinoid receptor activity, reducing inflammation and interacting with neurotransmitters ( 4 ).

For example, one study in rats found that CBD injections reduced pain response to surgical incision, while another rat study found that oral CBD treatment significantly reduced sciatic nerve pain and inflammation ( 5 , 6 ).

Several human studies have found that a combination of CBD and THC is effective in treating pain related to multiple sclerosis and arthritis.

An oral spray called Sativex, which is a combination of THC and CBD, is approved in several countries to treat pain related to multiple sclerosis.

One study of 47 people with multiple sclerosis examined the effects of taking Sativex for one month. The participants experienced improvements in pain, walking, and muscle spasms. Still, the study didn’t include any control group and placebo effects cannot be ruled out ( 7 ).

Another study found that Sativex significantly improved pain during movement, pain at rest and sleep quality in 58 people with rheumatoid arthritis ( 8 ).

Summary CBD, especially in combination with THC, may be effective in reducing pain associated with diseases like multiple sclerosis and rheumatoid arthritis.

Anxiety and depression are common mental health disorders that can have devastating impacts on health and well-being.

According to the World Health Organization, depression is the single largest contributor to disability worldwide, while anxiety disorders are ranked sixth (9).

Anxiety and depression are usually treated with pharmaceutical drugs, which can cause a number of side effects including drowsiness, agitation, insomnia, sexual dysfunction and headache ( 10 ).

What’s more, medications like benzodiazepines can be addictive and may lead to substance abuse ( 11 ).

CBD oil has shown promise as a treatment for both depression and anxiety, leading many who live with these disorders to become interested in this natural approach.

In one Brazilian study, 57 men received either oral CBD or a placebo 90 minutes before they underwent a simulated public speaking test. The researchers found that a 300-mg dose of CBD was the most effective at significantly reducing anxiety during the test.

The placebo, a 150-mg dose of CBD, and a 600-mg dose of CBD had little to no effect on anxiety ( 12 ).

CBD oil has even been used to safely treat insomnia and anxiety in children with post-traumatic stress disorder ( 13 ).

CBD has also shown antidepressant-like effects in several animal studies ( 14 , 15 ).

These qualities are linked to CBD’s ability to act on the brain’s receptors for serotonin, a neurotransmitter that regulates mood and social behavior.

Summary Using CBD has been shown to reduce anxiety and depression in both human and animal studies.

CBD may help reduce symptoms related to cancer and side effects related to cancer treatment, like nausea, vomiting and pain.

One study looked at the effects of CBD and THC in 177 people with cancer-related pain who did not experience relief from pain medication.

Those treated with an extract containing both compounds experienced a significant reduction in pain compared to those who received only THC extract ( 16 ).

CBD may also help reduce chemotherapy-induced nausea and vomiting, which are among the most common chemotherapy-related side effects for those with cancer ( 17 ).

Though there are drugs that help with these distressing symptoms, they are sometimes ineffective, leading some people to seek alternatives.

A study of 16 people undergoing chemotherapy found that a one-to-one combination of CBD and THC administered via mouth spray reduced chemotherapy-related nausea and vomiting better than standard treatment alone ( 18 ).

Some test-tube and animal studies have even shown that CBD may have anticancer properties. For example, one test-tube study found that concentrated CBD induced cell death in human breast cancer cells ( 19 ).

Another study showed that CBD inhibited the spread of aggressive breast cancer cells in mice ( 20 ).

However, these are test-tube and animal studies, so they can only suggest what might work in people. More studies in humans are needed before conclusions can be made.

Summary Though CBD has been shown to help reduce symptoms related to cancer and cancer treatment, and may even have cancer-fighting properties, more research is needed to assess its efficacy and safety.

Acne is a common skin condition that affects more than 9% of the population ( 21 ).

It is thought to be caused by a number of factors, including genetics, bacteria, underlying inflammation and the overproduction of sebum, an oily secretion made by sebaceous glands in the skin ( 22 , 23).

Based on recent scientific studies, CBD oil may help treat acne due to its anti-inflammatory properties and ability to reduce sebum production.

One test-tube study found that CBD oil prevented sebaceous gland cells from secreting excessive sebum, exerted anti-inflammatory actions and prevented the activation of “pro-acne” agents like inflammatory cytokines ( 24 ).

Another study had similar findings, concluding that CBD may be an efficient and safe way to treat acne, thanks in part to its remarkable anti-inflammatory qualities ( 25 ).

Though these results are promising, human studies exploring the effects of CBD on acne are needed.

Summary CBD may have beneficial effects on acne due to its anti-inflammatory qualities and its ability to control the overproduction of sebum from the sebaceous glands.

Researchers believe that CBD’s ability to act on the endocannabinoid system and other brain signaling systems may provide benefits for those with neurological disorders.

In fact, one of the most studied uses for CBD is in treating neurological disorders like epilepsy and multiple sclerosis. Though research in this area is still relatively new, several studies have shown promising results.

Sativex, an oral spray consisting of CBD and THC, has been proven to be a safe and effective way to reduce muscle spasticity in people with multiple sclerosis.

One study found that Sativex reduced spasms in 75% of 276 people with multiple sclerosis who were experiencing muscle spasticity that was resistant to medications ( 26 ).

Another study gave 214 people with severe epilepsy 0.9–2.3 grams of CBD oil per pound (2–5 g/kg) of body weight. Their seizures reduced by a median of 36.5% ( 27 ).

One more study found that CBD oil significantly reduced seizure activity in children with Dravet syndrome, a complex childhood epilepsy disorder, compared to a placebo ( 28 ).

However, it’s important to note that some people in both these studies experienced adverse reactions associated with CBD treatment, such as convulsions, fever and fatigue.

CBD has also been researched for its potential effectiveness in treating several other neurological diseases.

For example, several studies have shown that treatment with CBD improved quality of life and sleep quality for people with Parkinson’s disease ( 29 , 30 ).

Additionally, animal and test-tube studies have shown that CBD may decrease inflammation and help prevent the neurodegeneration associated with Alzheimer’s disease ( 31 ).

In one long-term study, researchers gave CBD to mice genetically predisposed to Alzheimer’s disease, finding that it helped prevent cognitive decline ( 32 ).

Summary Though research is limited at this time, CBD has been shown to ease symptoms related to epilepsy and Parkinson’s disease. CBD was also shown to reduce the progression of Alzheimer’s disease in test-tube and animal studies.

Recent research has linked CBD with several benefits for the heart and circulatory system, including the ability to lower high blood pressure.

High blood pressure is linked to higher risks of a number of health conditions, including stroke, heart attack and metabolic syndrome ( 33 ).

Studies indicate that CBD may be able to help with high blood pressure.

One recent study treated nine healthy men with one dose of 600 mg of CBD oil and found it reduced resting blood pressure, compared to a placebo.

The same study also gave the men stress tests that normally increase blood pressure. Interestingly, the single dose of CBD led the men to experience a smaller blood pressure increase than normal in response to these tests ( 34 ).

Researchers have suggested that the stress- and anxiety-reducing properties of CBD are responsible for its ability to help lower blood pressure.

Additionally, several animal studies have demonstrated that CBD may help reduce the inflammation and cell death associated with heart disease due to its powerful antioxidant and stress-reducing properties.

For example, one study found that treatment with CBD reduced oxidative stress and prevented heart damage in diabetic mice with heart disease ( 35 ).

Summary Though more human studies are needed, CBD may benefit heart health in several ways, including by reducing blood pressure and preventing heart damage.

CBD has been studied for its role in treating a number of health issues other than those outlined above.

Though more studies are needed, CBD is thought to provide the following health benefits:

  • Antipsychotic effects: Studies suggest that CBD may help people with schizophrenia and other mental disorders by reducing psychotic symptoms ( 36 ).
  • Substance abuse treatment: CBD has been shown to modify circuits in the brain related to drug addiction. In rats, CBD has been shown to reduce morphine dependence and heroin-seeking behavior ( 37 ).
  • Anti-tumor effects: In test-tube and animal studies, CBD has demonstrated anti-tumor effects. In animals, it has been shown to prevent the spread of breast, prostate, brain, colon and lung cancer ( 38 ).
  • Diabetes prevention: In diabetic mice, treatment with CBD reduced the incidence of diabetes by 56% and significantly reduced inflammation ( 39 ).

Summary Some studies suggest that CBD may help with diabetes, substance abuse, mental disorders and certain types of cancers. However, more research in humans is needed.

Though CBD is generally well tolerated and considered safe, it may cause adverse reactions in some people.

Side effects noted in studies include ( 40 ):

  • Diarrhea
  • Changes in appetite and weight
  • Fatigue

CBD is also known to interact with several medications. Before you start using CBD oil, discuss it with your doctor to ensure your safety and avoid potentially harmful interactions ( 41 ).

This is especially important if you take medications or supplements that come with a “grapefruit warning.” Both grapefruit and CBD interfere with cytochromes P450 (CYPs), a group of enzymes that are important to drug metabolism (42).

One study performed on mice showed that CBD-rich cannabis extracts have the potential to cause liver toxicity. However, some the mice in the study were force-fed extremely large doses of the extract (43).

Summary Although CBD is generally considered safe, it can cause adverse reactions like diarrhea and fatigue in some people. It may also interfere with certain medications.

CBD oil has been studied for its potential role in easing symptoms of many common health issues, including anxiety, depression, acne and heart disease.

For those with cancer, it may even provide a natural alternative for pain and symptom relief.

Research on the potential health benefits of CBD oil is ongoing, so new therapeutic uses for this natural remedy are sure to be discovered.

Though there is much to be learned about the efficacy and safety of CBD, results from recent studies suggest that CBD may provide a safe, powerful natural treatment for many health issues.

If you’re interested in trying CBD, you can purchase many products online, including gummies, oils, and lotions.

Is CBD Legal? Hemp-derived CBD products (with less than 0.3 percent THC) are legal on the federal level, but are still illegal under some state laws. Marijuana-derived CBD products are illegal on the federal level, but are legal under some state laws. Check your state’s laws and those of anywhere you travel. Keep in mind that nonprescription CBD products are not FDA-approved, and may be inaccurately labeled.

Cannabidiol, or CBD, is a chemical compound in marijuana with a variety of uses. Here are 7 benefits of CBD oil.

Best CBD Oil for High Blood Pressure (Hypertension) – November 2020

Does CBD help lower high blood pressure?

  • In a 2017 study published in the JCI Insight Journal, researchers concluded that a single dose of CBD reduced resting blood pressure and the blood pressure response to stress (1 ) .
  • However, researchers believed that the results were a reflection of CBD’s anti-anxiety and analgesic effects (2 ) .
  • Authors of a 2019 study published in the Brazilian Journal of Psychiatry demonstrated that CBD reduced the response to stressful environmental factors when given in the optimal dosage (3 ) .
  • Given that most of the results from blood pressure-related studies done on CBD have been gathered through tests that involve either healthy volunteers or animals, recent research on ill human subjects is still lacking.
  • The American Heart Association (AHA) says that with high blood pressure, the best prevention is knowing the blood pressure reading and making changes that matter to prevent and manage the condition (4 ) .

Best CBD Oils For High Blood Pressure

A sublingual application of CBD oil tincture may be the best way to take CBD for high blood pressure as it gets absorbed by the body fast, and the effects are felt for an extended period.

Here are products that are recommended to use to help with issues related to high blood pressure.

  1. Editor’s Pick:CBD Oil by Spruce
  2. Best Natural Alternative:CBD Oil Tincture Natural by cbdMD
  3. Most Pure:Full Spectrum CBD Oil by CBDistillery
  4. Best Organic:Full Spectrum Hemp Oil by Nuleaf Naturals
  5. Best Value:Super Good Vibes CBD Oil by Sabaidee

Spruce 750mg Lab Grade CBD Oil

Specifically formulated to be more palatable to CBD users
Overall Clinical Score

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

  • &nbsp Mid-strength
  • &nbsp Natural peppermint flavor
  • &nbsp Made from 100% organic and natural ingredients
  • &nbsp No other flavors
Discount pricing available? 20% Off Coupon Code: CBDCLINICALS
Source

cbdMD CBD Oil Tincture Natural 1500mg

Uses USA hemp that is grown on non-GMO farms, and is both vegan and gluten-free
Overall Clinical Score

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

  • &nbsp Various delicious flavors to choose from
  • &nbsp Has vegan, organic, and gluten-free ingredients
  • &nbsp Free shipping for this particular product within USA
  • &nbsp World-class customer service team
  • &nbsp cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Discount pricing available? 15% Off Coupon Code: cbdMD15
Source

CBDistillery Full Spectrum CBD Oil

Reap all of the benefits of cannabis plant without any potentially intoxicating effects.
Overall Clinical Score

CBDistillery’s Full Spectrum Oil Tinctures combine the powers of CBD oil and other naturally occurring plant proteins, minerals, vitamins, and more so that you can get all of the benefits of the cannabis plant without any potentially intoxicating effects.

  • &nbsp 60-Day Satisfaction Guarantee
  • &nbsp Various strengths
  • &nbsp Oil extracted from aerial plant parts of US grown industrial hemp
  • &nbsp Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
  • &nbsp Dropper is a bit shaky
Discount pricing available? CBDCLINICALS15
Source

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil

Perfect for anyone who are looking for CBD products that promote a healthy body and mind.
Overall Clinical Score

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

  • &nbsp Pure CBD hemp
  • &nbsp All natural
  • &nbsp Approximately 300 drops total
  • &nbsp No other flavors
Discount pricing available? 20% Off Coupon Code: CBDCLINICALS20
Source

Sabaidee Super Good Vibes CBD Oil

4x the strength of a regular cbd oil
Overall Clinical Score

Super Good Vibes CBD Oil provides the purest and highest quality Cannabidiol (CBD) on the market as well as other high quality phytocannabinoids, terpenes, vitamins, omega fatty acids, trace minerals, and other beneficial for your health elements, which all work together to provide benefits.

  • &nbsp Extra strong
  • &nbsp Significant benefits with just a few drops
  • &nbsp 100% Natural ingredients
  • &nbsp No other flavors
Discount pricing available? 15% Off Coupon Code: CBDCLINICALS15
Source

Why People Are Taking CBD for High Blood Pressure

According to the Centers for Disease Control and Prevention (CDC), high blood pressure can harden and narrow the arteries, which decreases the flow of blood and oxygen to the heart, leading to heart disease (5 ) .

In a 2015 study conducted by researchers from the University of Nottingham Royal Derby Hospital in the UK, CBD was shown to be a potent vascular relaxant to human gut arteries, suggesting its potential benefits to dilate blood vessels and increase blood flow (6 ) .

How CBD Oil Works to Help with High Blood Pressure

CBD has been shown to possess potential benefits that may help lower blood pressure by addressing health issues that cause blood pressure to rise.

CBD’s Anti-Anxiety Effects

Some factors linked to high blood pressure are anxiety and lack of sleep.

In a 2019 study published in The Permanente Journal , sleep and anxiety scores were measured in human subjects, and the findings showed that CBD could hold benefits for anxiety-related disorders (7 ) .

In another study , which was published in the Journal of Alternative and Complementary Medicine in 2019, CBD was shown to help in the treatment of post-traumatic stress disorder (PTSD) (8 ) .

The relaxation response can reduce blood pressure in people with hypertension, as indicated in the results of a study published in the Journal of Alternative and Complementary Medicine in 2018 (9 ) .

CBD as a Vasodilator

As a natural vasodilator, CBD may help improve positive cardiovascular health by widening the blood vessels to allow smooth blood flow.

CBD’s role as a vasodilator was highlighted in a double-blind, placebo-controlled, and randomized crossover study conducted by researchers from the Royal Derby Hospital Centre and Oxford Centre for Diabetes, Endocrinology & Metabolism, Churchill Hospital in the UK in 2017 (10 ) .

In the said study , researchers explored the connection between CBD and a reduction in blood pressure, and they found that a single dose of CBD oil significantly lowered blood pressure in a small study of healthy human volunteers, both under stress and at rest.

However, the authors also noted that “there are no dedicated studies in humans to date, to our knowledge, looking at the effect of CBD on either resting cardiovascular measurement or on the responses to stress, with continuous monitoring of cardiovascular parameters.”

CBD’s Anti-Inflammatory Effects

Studies conducted by researchers from the University of South Carolina School of Medicine in 2009 also reveal that CBD possesses anti-inflammatory properties. Since inflammation can cause high blood pressure or vice versa, eliminating inflammation may help alleviate high blood pressure (11 ) .

However, inflammation may be a result of other diseases as well. Thus, leading a healthy lifestyle while using CBD oil is advised.

CBD vs. Cortisol Secretion

Cortisol, the “stress hormone,” is released by the body under stress. An elevated cortisol level may cause a physical stress response in the body that could raise blood pressure.

Results from a 1993 study published in the Brazilian Journal of Medical and Biological Research suggested that CBD interferes with cortisol secretion (12 ) . Thus, if high blood pressure is due to elevated stress levels, CBD oil may theoretically be beneficial.

CBD and The Dynamics of Blood Flow

In a systematic review and meta-analysis published in the Frontiers in Pharmacology Journal in 2017, the authors examined the hemodynamic (blood flow) effects of CBD (13 ) .

The authors of the said study concluded that CBD might be used as a potential remedy for cardiovascular disorders, such as hypertension and stroke.

However, they found no evidence that CBD provides similar results under non-stressful conditions.

Much of these data were from mice, and results from human studies on the effects of CBD on hemodynamics is still limited.

CBD Interacts with Neurotransmitters

Results of a 2017 study published in the Cannabis and Cannabinoid Research Journal show how a neurotransmitter, such as anandamide, plays a critical role in the functioning of the heart (14 ) .

Data from the study has shown that CBD oil regulates the reuptake of essential heart neurotransmitters that control the cardiovascular system.

CBD’s Neuroprotective Effects

A study published in the British Journal of Clinical Pharmacology in 2013 has shown how CBD allows blood flow in the vessels to maintain healthy blood pressur e in animal models (15 ) .

The review has also presented evidence of the positive effects of CBD in the cardiovascular system.

Data from the said study illustrate that CBD potentially provides neuroprotective effects, which may help protect the brain against stroke.

The findings also suggest that CBD can induce a healthy heart rhythm after an ischemic attack, which is caused by a build-up or blockage in the arteries. Thus, CBD was shown to potentially improve heart performance immediately after a heart attack in non-human models.

Although the results demonstrate that the cardiovascular system is a valid therapeutic target for CBD, the target sites of action for CBD remain to be established for most of the responses.

As more and more studies and clinical trials are conducted in human subjects, CBD oil’s efficacy in treating high blood pressure would become more explicit.

The Pros and Cons of CBD Oil for High Blood Pressure

The Pros
  • CBD “is generally well tolerated with a good safety profile,” as the World Health Organization (WHO) states in a critical review (16 ) .
  • CBD’s feasibility as a potential remedy to hypertension-related symptoms has been shown in the numerous studies stated above.
The Cons
  • Studies are too limited to determine whether or not CBD is an effective treatment for conditions other than the ones approved by the U.S. Food and Drug Administration (FDA).
  • As with the use of any natural chemical compound, there are risks involved in using CBD. According to the Mayo Clinic, possible side effects include drowsiness, dry mouth, diarrhea, fatigue, and reduced appetite (17 ) .
  • Most of the results from blood pressure-related studies done on CBD have been gathered through tests that involve healthy volunteers, very low population sizes, or animals, like that of a study done on rats (18 ) .

Given the limited scope, facts cannot be established that the results of previous investigations would be comparable with that of tests involving ill human subjects.

  • CBD has been shown to alter how the body metabolizes certain medications, as a 2017 research reveals (19 ) . With results published in the Cannabis and Cannabinoid Research Journal , the research suggests that the combination of CBD with other high blood pressure medications has the potential to alter the blood concentrations of either substance.

Results of a study published in the Medicines Journal indicated that the CYP450 family of enzymes is responsible for metabolizing several phytocannabinoids (cannabinoids that exist naturally in the cannabis plant), including CBD (20 ) .

If one is already on high blood pressure medication, taking CBD in combination with the prescribed drug can lower blood pressure too much. Blood pressure that is too low is as bad as blood pressure that is too high.

  • The lack of regulation makes it difficult to determine whether the CBD gummies, tinctures, patches, balms, and gelcaps contain what the product label claims.

A 2017 review published in the Journal of the American Medical Association revealed labeling inaccuracies among CBD products. Some products had less CBD than stated, while others had more (21 ) .

Experts recommend speaking with a physician before adding CBD onto the medications that are currently taken. The doctor may want to reduce the dosage strength of the blood pressure prescription before incorporating CBD oil into the daily regimen of an individual.

How CBD Oil Compares to Alternative Treatments for High Blood Pressure

Although the prescription medications currently available for hypertension are effective, they bring about side effects, which can make the treatment an unpleasant experience.

Cannabidiol (CBD), on the other hand, is a natural alternative that has shown to have little side effects, and the side effects of CBD are less common than the effects associated with most pharmaceutical medications used to treat high blood pressure.

How To Choose The Right CBD for High Blood Pressure

The best CBD oil product to use for high blood pressure is CBD tincture. By taking a sublingual dosage, the optimum level of CBD gets absorbed into the system, which means CBD works the fastest, and the effects are probably felt the longest.

However, regardless of the form of CBD product one chooses, he or she must employ careful consideration in choosing the best CBD oil for high blood pressure that is right for him or her.

The following factors are essential to ensure the safety and reliability of the CBD products purchased:

  1. Research on the exact legal stipulations applicable to CBD in the area where it would be purchased and used.
  2. Purchase only from legitimate and reliable big brands. The majority of companies that manufacture the best CBD oil products grow their hemp from their farm, or they purchase from licensed hemp producers.
  3. When buying from an online store, do some research on product reviews first. When buying from a physical store or dispensary, check whether the store is authorized by the government to sell CBD.
  4. One important thing to look for in CBD products is certification codes. Several certification authorities approve certain products only after some thorough screening tests.
  5. Compare company claims about their products’ potency with that of the third-party lab reports.
  6. Consulting with a trusted medical professional who is experienced in CBD use is ideal before purchasing any CBD product .

CBD Dosage For High Blood Pressure

In a 2019 review, Mayo Clinic suggests CBD dosages based on publications, scientific research, traditional use, and expert opinion (22 ) .

The doses and duration of treatment depend primarily on the illness. However, there is no specific dose recommended for high blood pressure.

Results of a 2017 study published in the Cannabis and Cannabinoid Research Journal provided evidence that a dosage of up to 1,500 mg of CBD a day is well-tolerated by humans (23 ) .

The authors of the study also found that at lower doses, CBD showed physiological effects that could potentially help promote and maintain health, including antioxidative, anti-inflammatory, and neuroprotection effects.

Following the dosing instructions on the CBD product of choice and starting with a low dose are the best course of action for those who would like to try CBD. Taking high doses at the beginning may bring about adverse reactions in the user.

As with any medication, the dose would depend on the metabolism, genetics, size, and body weight of a person.

How to Take CBD Oil for High Blood Pressure

There are various ways to consume CBD oil, and the delivery format would most likely depend on personal preferences and lifestyle.

CBD Oil Capsules and Edibles

CBD oil capsules and edibles, such as brownies, gummies, and lozenges, are a convenient and straightforward way to take CBD oil, especially for beginners.

This format is easy to work into a routine, and the dose is consistent. Depending on the metabolism of an individual, the effects can last between 6 and 12 hours. Thus, one dose is probably all that is needed during the day.

However, consuming CBD oil can delay its effects as it has to pass through the digestive system before it gets absorbed into the bloodstream. Given that the effects of the CBD oil could take at least 20 minutes to an hour to appear, CBD oil capsules and edibles do not provide immediate relief.

CBD Oil Tinctures or Drops

CBD oil tinctures or drops are a practical option for those who seek faster results and maximum dosage control.

Tinctures and drops are administered under the tongue, through which the CBD oil is absorbed directly into the bloodstream.

Place the desired quantity of drops under the tongue using a dropper, and then let the CBD oil stay in place for at least 60 seconds. Once 60 seconds have passed, swallow the CBD oil.

Sublingual application allows for results to be experienced within 30 to 60 minutes after its use, and the effects can be felt for 4 to 6 hours.

Since tinctures and drops are convenient and easy to store and travel with, they can be effortlessly administered when needed.

However, one significant drawback to CBD oil tinctures and drops is the taste, as not everyone appreciates the natural, earthy, and sometimes bitter flavor of hemp.

Although some products come in various flavors to compensate for the unpleasant taste, the addition of sugar and chemicals may be something that one wants to avoid.

CBD Oil Vapes

CBD oil vapes are one of the accelerated ways to get CBD into the body since it enters the bloodstream through the lungs, without going through the digestive system.

When vaping CBD oil, effects can be felt in minutes. However, the effects last only for 30 minutes to an hour or two.

Also, with vaping, it is difficult to determine precisely how much CBD is in each draw. Although labels for CBD oil vape products usually indicate the amount per inhale, the amount may vary in individuals. Thus, getting the dose right requires a bit of experimentation at first.

Understanding High Blood Pressure

Blood pressure is influenced by how much blood the heart pumps, how hard it pumps, and the resistance to blood flow in the arteries.

According to Mayo Clinic, the higher the amount of blood the heart pumps and the narrower the arteries, the higher the blood pressure (24 ) .

The narrowing and blocking of blood vessels that is caused by high blood pressure, or hypertension, affects heart health by increasing the risk of developing heart failure.

What A Blood Pressure Reading Means

When the doctor measures blood pressure, the reading is given in two numbers. The first number, referred to as systolic blood pressure, is the pressure caused by the heart contracting and releasing blood. The second number, called diastolic blood pressure, is the pressure when the heart relaxes and fills with blood.

The blood pressure reading is given as the systolic blood pressure number over the diastolic blood pressure number, such as 135/70.

A normal blood pressure reading for adults is 120/80, according to the American Heart Association (AHA) (25 ) .

Are There High Blood Pressure Symptoms?

The American Heart Association (AHA) calls high blood pressure a “silent killer.” An individual can have high blood pressure for years without any indications (26 ) .

Most people with high blood pressure do not exhibit symptoms, even though blood pressure readings rise to critically-high levels.

Meanwhile, AHA says, some people with high blood pressure may experience shortness of breath, headaches, or nosebleeds. However, these symptoms are not specific and do not occur until high blood pressure has reached a life-threatening stage.

Still, even in the absence of symptoms, damage to the heart and blood vessels continues and can be detected, AHA says .

The agency warns that undetected or unregulated high blood pressure intensifies the risk of severe health problems, including strokes and heart attacks (27 ) .

High blood pressure typically develops over several years, and it eventually affects almost everyone (28 ) .

The National Institute on Aging (NIA) states that high blood pressure is a critical health issue that is typical among older people (29 ) .

Fortunately, it is not difficult to detect high blood pressure. One can work with a doctor to control the condition once diagnosed.

To learn more about the studies on blood pressure, go to ClinicalTrials.gov or PubMed.gov (30 ) .

Traditional Medications for High Blood Pressure

Doctors often prescribe one or more of the following pharmaceutical drugs to people dealing with high blood pressure (31 ) :

  • Diuretics, like Diuril and Lozol, increase urination which reduces sodium and fluid in the body. Because diuretics lower blood volume, they help lower blood pressure. However, one side effect of diuretics can be a loss of potassium, which is needed for proper muscular movement.
  • Angiotensin II receptor blockers (ARBs) like Diovan, which, as vasodilators, dilate blood vessels. Their potential side effects include skin rashes, swelling mouth, joint and back pain, flu-like symptoms, nausea, headaches, and diarrhea.
  • Metoprolol beta-blockers, like Toprol-XL and Lopressor, slow the heart rate. However, they can cause diarrhea, constipation, vomiting, fatigue, anxiety, depression, insomnia, shortness of breath, and decreased libido.
  • Angiotensin-converting enzyme (ACE) inhibitors like Vasoctec and Benazepril prevent the contraction of blood vessels. Some adverse side effects may include skin rash, swelling mouth, dry cough, headaches, dizziness, and diarrhea.

According to an article published in MedlinePlus by the U.S. National Library of Medicine, high blood pressure medicines may cause some common side effects, such as diarrhea or constipation, dizziness, erection problems, fatigue, nausea or vomiting, skin rash, and weight loss or gain without trying (32 ) .

Sometimes, a person may need to take more than one type of drug to manage blood pressure.

Although a single drug would often be used initially, two drugs could be started for stage 2 high blood pressure.

The AHA describes stage 2 hypertension as the stage when blood pressure consistently ranges at 140/90 mm Hg or higher (33 ) .

People taking medications for hypertension are also warned that mixing beta-blockers and angiotensin II receptor antagonists must only be done at the recommendation of a physician since the combination can lead to acute renal failure, as a 2013 study published in the Hypertension Research Journal suggests (34 ) .

Lifestyle Changes to Help Prevent High Blood Pressure

Using medications as prescribed and making lifestyle changes can enhance the quality of life and reduce the risk of hypertension, says the American Heart Association (AHA) (35 ) . These changes include:

  • Eating a healthy diet that is low in fat, cholesterol, and salt to prevent further plaque build-up in the arteries.
  • Exercising regularly to strengthen your heart. This activity could be something as simple as taking a 30-minute walk each day.
  • Engaging in activities that help manage stress, such as meditation, journaling, making art, and seeing a therapist.

What to Know About CBD Oil

CBD oil contains CBD , or cannabidiol , as its primary active ingredient. Cannabidiol is associated with the previously mentioned benefits, including controlling blood pressure.

Comparing CBD and THC

CBD comes from cannabis and is naturally found in hemp plants. CBD is one of more than 100 cannabinoids that occur naturally within the plant. This compound is also commonly used to produce CBD hemp oil supplements.

Hemp seed oil is produced by extracting the oil from the seeds of the hemp plant itself. This oil is abundant in nutrients, such as omega-3 and omega-6 fatty acids, making it ideal for digestion. Although some people refer to “hemp extract” as hemp oil, the term “hemp oil” is synonymous with the term “hemp seed oil.”

Chemical compounds in cannabis, called cannabinoids, have shown various potential benefits by activating the body’s endocannabinoid system (ECS), which is involved in regulating a variety of functions including sleep, appetite, pain and immune system response (36 ) .

The body produces endocannabinoids, which are neurotransmitters that bind to cannabinoid receptors in the nervous system.

The medicinal efficacy of cannabis can be optimized by incorporating the various cannabinoids, flavonoids, and terpenes that are intrinsic components of cannabis plants.

CBD is non-psychoactive, contrasting with THC (tetrahydrocannabinol), another primary cannabinoid. THC is the most significant factor contributing to the high associated with using cannabis.

Consuming CBD without any THC does not produce those effects, which means that nearly everyone should be able to function as they usually do when taking CBD.

The lack of high allows users to continue with work, school, and other commitments without a decrease in performance. It also makes CBD oil safe to take , even for those who must pass regular or random drug tests.

CBD oil must not contain any THC for CBD to be non-psychoactive. Products containing CBD isolates do not have THC, while full-spectrum CBD products do.

Any product that one buys should also state the percentage of THC, information which one can also get from its certificate of analysis.

Other Health Benefits of CBD Oil

Here are some of the more critical benefits associated with cannabidiol .

Treating Seizures

CBD can help treat some of the worst types of seizure disorders that exist, including Lennox-Gastaut syndrome and Dravet syndrome, both of which affect children and do not typically respond to traditional medications for treating seizures (37 ) .

Even the U.S. Food and Drug Administration (FDA) recognizes the ability of CBD to treat seizure disorders (38 ) . The first cannabis-derived medication it approved is Epidiolex, which treats these conditions. That medication contains CBD.

Treating Anxiety Disorders and Depression

Those who suffer from anxiety may experience relief with CBD. Results from a 2019 study published in the Brazilian Journal of Psychiatry showed CBD’s anxiolytic effect on public speaking, and there is plenty of anecdotal evidence (39 ) .

In another study , which was published in the Journal of the American College of Cardiology , CBD was shown to attenuate oxidative stress, as well as cardiac dysfunction, fibrosis, and cell death in a mouse model (40 ) .

Treating Pain

One of the most popular uses of CBD oil is its ability to reduce chronic pain . Animal studies, like the study published in the European Journal of Pain in 2016, show that topically applied CBD may theoretically help provide pain relief and reduce inflammation from arthritis (41 ) .

In another study published in the Journal of Experimental Medicine , CBD was shown to reduce neuropathic pain (42 ) . This finding is crucial as it is one of the hardest types of pain to treat.

Some countries approve oral sprays like Sativex, which contains both CBD and THC (43 ) . This spray effectively treats the pain associated with multiple sclerosis (MS), a potentially disabling disease of the brain and spinal cord (central nervous system).

However, as Sativex and certain medications may trigger a drug interaction, experts advise consulting with a doctor first about all the prescription, over-the-counter (non-prescription), and herbal medications that are being taken before starting to use Sativex oral spray.

Protecting the Brain

CBD research , conducted on animal models and humans and published in the Surgical Neurology International in 2018, has shown numerous therapeutic properties for brain function and protection, both by its effect on the endocannabinoid system directly and by influencing endogenous cannabinoids (44 ) .

Researchers in a study published in the Journal of Psychopharmacology noted a possible effect of CBD in improving the quality of life in patients with Parkinson’s disease without adverse outcomes (45 ) .

Studies analyzed in a 2017 review conducted by experts from the Western Sydney University in Australia also provided proof of principle for the therapeutic benefits that CBD and possibly CBD-THC combinations may provide (46 ) .

Data suggest that these combinations may help with the therapy of Alzheimer’s disease (named after Dr. Alois Alzheimer, who noted the symptoms in 1906).

May Help Fight Cancer

A 2010 study published by the American Association for Cancer Research showed a CBD-induced cell death of breast cancer cells, suggesting that the use of CBD oil may also suppress tumor growth (47 ) .

Research on cannabinoids published in the Future Medicinal Chemistry demonstrates that cannabinoids may also prove beneficial in certain types of cancers that are activated by chronic inflammation (48 ) .

In such instances, cannabinoids, as anti-inflammatory agents, can either directly prevent tumor growth or suppress inflammation .

Meanwhile, in-depth research on CBD yields mixed results.

In a recent study published in the Bosnian Journal of Basic Medical Sciences , researchers recognized the antitumor effects of cannabinoids in various cancer types (49 ) .

However, these antitumor effects of cannabinoids have to prevail over their known immunosuppressive effects, which can potentially promote the production or formation of tumors.

Recent studies are still limited when it comes to CBD and cancer prevention. Longitudinal studies of humans using specific CBD products, controlling for frequency of use and dosing are needed.

Overcoming Substance Abuse

There is some evidence that using CBD may help those with addiction overcome their substance abuse.

Published in the Journal of Substance Abuse Treatment , results from a 2015 study conducted on animal models showed CBD reduced heroin-seeking behavior and reduced morphine dependence (50 ) .

The Legality of CBD Oil

The Cannabis sativa plant produces both hemp and marijuana. The difference between the two plants is the percentage of THC that they contain.

A cannabis plant that has 0.3 percent or less of THC content classifies as hemp, while a cannabis plant containing over 0.3 percent of THC is considered marijuana.

In the United States, cannabis-related laws are continually changing. Since marijuana and THC are on the list of controlled substances, they are currently prohibited under federal law (51 ) .

Meanwhile, confusion arises due to regulations that vary depending on whether the CBD is hemp-derived or extracted from marijuana. The former is legal at the federal level, while the latter is not.

Many states and Washington, D.C. have passed cannabis-related laws, making medical marijuana with high levels of THC legal. Still, marijuana may require a prescription from a licensed physician (52 ) .

Also, several states have made recreational use of marijuana and THC legal. One should be able to buy CBD in states where marijuana is legal for recreational or medical purposes.

NORML has information regarding state laws and penalties. (53 ) .

Individuals who possess cannabis-related products in a state where they are illegal or do not have a medical prescription in states where the products are legal for medical treatment could face legal penalties.

For a complete list of legal medical marijuana states and D.C., including the corresponding laws, fees, and possession limits, visit ProCon.org (54 ) .

Conclusion

According to the Centers for Disease Control and Prevention (CDC), about 75 million American adults, or 1 in 3 adults, have high blood pressure (55 ) . People with high blood pressure have a greater risk of heart disease and stroke, the leading causes of death in the United States.

CBD oil has shown to be a natural remedy to issues that could be linked to high blood pressure, such as stress and p a in (56) .

Meanwhile, using medications as prescribed and making lifestyle changes can enhance the quality of life and reduce the risk of hypertension, says the American Heart Association (AHA) (57 ) .

Still, before experimenting with different CBD products and dosages, speak to a doctor about a CBD treatment or using CBD oil for treating high blood pressure.

For anyone still looking for more information on CBD as a medical supplement, speaking with a cannabis doctor who specializes in the subject is the best course of action.

There is a wide range of products to choose from for those who are ready to decide which product and how they would like to take CBD oil to either address medical conditions or maintain general well-being.

A sublingual application of CBD oil tincture may be the best way to take CBD for high blood pressure as it gets absorbed by the body fast, and the effects are f