Best CBD Oil for Gastritis – November 2020
Does CBD Work for Gastritis?
- Research in 2020 revealed that cannabidiol (CBD) had anti-inflammatory effects in rodent models of intestinal inflammation (1) . Gastritis is an inflammation of the stomach lining (2) .
- A systematic review in 2019 suggested that CBD had anti-inflammatory and antioxidant properties (3) .
- A preclinical study in the British Journal of Pharmacology stated that CBD might be promising in alleviating vomiting and nausea caused by treatments, such as chemotherapy (4) . Vomiting and nausea are common gastritis symptoms (5) .
- Currently, the animal and human studies available focus on CBD’s effects on symptoms associated with gastritis.
- More research on CBD’s benefits on gastritis is warranted.
Spruce 750mg Lab Grade CBD Oil
Specifically formulated to be more palatable to CBD users
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Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.
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NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
Perfect for anyone who are looking for CBD products that promote a healthy body and mind.
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Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.
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Sabaidee Super Good Vibes CBD Oil
4x the strength of a regular cbd oil
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Super Good Vibes CBD Oil provides the purest and highest quality Cannabidiol (CBD) on the market as well as other high quality phytocannabinoids, terpenes, vitamins, omega fatty acids, trace minerals, and other beneficial for your health elements, which all work together to provide benefits.
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cbdMD CBD Oil Tincture Natural 1500mg
Uses USA hemp that is grown on non-GMO farms, and is both vegan and gluten-free
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cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.
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Why People Are Taking CBD for Gastritis
Commonly prescribed medications and over-the-counter drugs for gastritis include omeprazole, rabeprazole, lansoprazole, dexlansoprazole, esomeprazole, and pantoprazole (6) . These drugs are some of the most potent inhibitors of stomach acid.
However, these medications may have side effects , such as iron and B12 deficiency, increased risk of fractures, pneumonia, and Clostridium difficile infections (7) . They can also be quite expensive over the long-term.
Clostridium difficile infections may cause diarrhea and eventually develop into a life-threatening medical condition .
Doctors may also prescribe antacids to treat gastritis by neutralizing stomach acid and providing pain relief. However, these drugs may result in constipation or diarrhea (8) .
A 2020 study in the International Journal of Molecular Sciences outlined CBD’s role in preventing and treating gastrointestinal disorders, like irritable bowel syndrome (IBS) and gastrointestinal cancer (9) .
The study demonstrated CBD’s anti-inflammatory properties in mice models of intestinal inflammation.
Gastritis is a collective term that refers to the inflammation of the lining of the stomach (10) .
Research in the Journal of Molecular Medicine evaluated CBD’s effects on an inflammatory bowel disease like ulcerative colitis (11) .
The authors found that CBD had anti-inflammatory properties beneficial for the inflamed gut. They also reported that CBD, a “likely safe compound,” prevented experimental colitis in mice.
Despite CBD’s purported health benefits on the digestive tract , it is essential to note the side effects of CBD use. These effects include diarrhea, changes in appetite or weight, and tiredness (12) .
CBD for Inflammation
A 2019 review archived in the journal Antioxidants stated that CBD had anti-inflammatory and antioxidant properties (13) .
The authors also mentioned CBD’s promise in treating disorders associated with inflammation and oxidative stress, such as cancer, cardiovascular, metabolic, and neurodegenerative diseases.
Another study documented in the journal Future Medicinal Chemistry discussed CBD’s effects on non-obese and diabetes-prone female rodents (14) .
The researchers found that CBD had anti-inflammatory effects that could help prevent type 1 diabetes.
CBD for Nausea
Common symptoms of gastritis include nausea and vomiting (15) .
Preclinical research showed that CBD might be useful in treating vomiting and nausea caused by chemotherapy and other treatments (16) .
A study archived in the British Journal of Clinical Pharmacology evaluated the effects of a dose containing CBD and tetrahydrocannabinol (THC) on patients with chemotherapy-induced nausea and vomiting (17) .
The researchers found that CBD and THC were well-tolerated and had antiemetic (vomit-preventing) properties.
They also observed that patients who received the cannabis-based medicine had better protection against delayed chemotherapy-induced nausea and vomiting.
CBD and THC are derived from the Cannabis sativa plant. However, unlike CBD, THC may get individuals high because of its psychoactive properties.
THC mainly comes from marijuana, a variant of the cannabis plant. Despite THC’s suggested benefits, medical marijuana use is not legal in the entire United States (18) .
CBD for Ulcers
Untreated gastritis may result in stomach ulcers and bleeding or stomach perforation (19) .
A 2018 study in the journal Phytotherapy Research evaluated CBD’s effects on oral wound healing (20) .
Standardized ulcers were induced in 60 rats. They were injected with 0mg (control), 5mg, and 10mg of CBD per kilogram of each rat’s body weight daily.
The researchers discovered that CBD had anti-inflammatory effects on the early phase of wound healing. However, they noted that their findings were insufficient to conclude that CBD use could improve oral traumatic lesions.
CBD as a Painkiller Substitute
The regular use of painkillers and nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, may result in gastritis and ulcers (21) .
Meanwhile, s tudies showed that CBD products might have analgesic effects. Hence, they may be used as substitutes for painkillers.
A study published in the journal Postgraduate Medicine revealed that CBD improved chronic pain in participants using opioids for pain management (22) .
One hundred thirty-one patients were included in the study. The researchers found that half of the study sample was able to reduce opioid use eight weeks after adding CBD to their medication regimen.
Participants who used CBD reported improvements in their quality of life. Their chronic pain and sleep quality also improved.
In another research, results indicated that CBD had analgesic and anxiolytic (anxiety-reducing) effects (23) .
Three hundred ninety-seven individuals were prescribed CBD. Participants who had non-cancer pain reported improvements in their pain.
Meanwhile, those who had mental health symptoms experienced alleviation of their depression and anxiety symptoms.
CBD was well-tolerated, and the participants did not report any adverse effects. Other CBD benefits include improved sleep and appetite.
How CBD Oil Works to Alleviate Symptoms of Gastritis
A study documented in the PLOS One Journal evaluated how CBD purportedly reduces intestinal inflammation (24) .
Eighteen participants were included in the study. The results revealed that CBD might interfere with enteroglial-mediated interactions in an intestinal inflammatory environment.
Enteric glial cells make up the enteric nervous system, a regulatory system responsible for gastrointestinal function (25) .
According to the study, CBD was involved in the downregulation of the protein S100B, resulting in reduced intestinal damage during acute and intestinal inflammation.
S100 proteins have a vital role in mediating innate and acquired immune response s (26) . These responses significantly contribute to the development of chronic inflammatory diseases.
It is believed that CBD’s interaction with the endocannabinoid system (ECS) may be related to its anti-inflammatory properties.
The ECS has an essential role in maintaining the body’s natural harmony. To fulfill this function, it interacts with several organs and systems in the body, such as the endocrine and immune systems (27) .
A study conducted in 2019 outlined the role of CBD and the ECS’ cannabinoid receptors in inflammation (28) .
Research found that CBD was a weak agonist of the cannabinoid receptor 1 ( CB1 receptor ) in humans and mice. It also stated that CBD demonstrated inverse agonism of the cannabinoid receptor 2 (CB2 receptor) .
An agonist is a substance that mimics another substance’s action, stimulating an action (29) .
The researchers found that the activation of cannabinoid receptor 2 reduces oxidative stress and inflammation.
They also found that CBD’s anti-inflammatory activity involved the reduction of cytokine levels, the inhibition of T-cell proliferation, the induction of T-cell apoptosis, and the migration of immune cells.
Cytokines are molecules that direct cell movement to sites of inflammation, trauma, and infection (30) .
T cells contribute to sustained inflammation by producing proinflammatory cytokines (31) .
Apoptosis is programmed cell death vital in removing unnecessary or abnormal cells (32) .
The Pros and Cons of CBD Oil for Gastritis
- Previous studies showed CBD’s positive effects on symptoms associated with gastritis and other conditions related to the digestive system .
- Compared with conventional drugs prescribed for gastritis, CBD’s safety profile is more favorable (33) .
- There are no reported cases of human or animal dependence on CBD (34) . Hence, individuals considering using CBD to treat their gastritis should not worry about developing a dependence on the substance.
- Researchers should further investigate CBD’s effects on gastritis.
- Despite the benefits of CBD , it still has side effects, such as diarrhea, tiredness, and changes in weight or appetite (35) .
- Policies from the United States Food and Drug Administration (US FDA ) do not support CBD as therapy for medical conditions other than epilepsy.
How CBD Oil Compares to Alternative Treatments for Gastritis
A study archived in the Sultan Qaboos University Medical Journal investigated honey’s antibacterial effects on the bacterium Helicobacter pylori ( H. pylori) , the common cause of several digestive issues, such as gastritis and a very common contributor to the development of gastric and duodenal ulcers (36) .
The researchers concluded that some honey brands had antibacterial properties useful in treating H. pylori infections.
They also noted that when honey was used with antibiotics, such as clarithromycin and amoxicillin, there was no synergy or antagonism.
They recommend that honey may be useful as an adjunct therapy. It helps reduce the elimination time of H. pylori bacteria from the stomach lining of individuals with gastritis or duodenal ulcer.
Similarly, CBD was found to have antibacterial properties. Research in 2019 reported CBD’s efficacy in killing a range of Gram-positive bacteria (37) .
The researchers suggested that, given CBD’s anti-inflammatory properties and proven safety in humans, the substance held promise as a new antibiotic.
They also noted how CBD retained its efficacy against bacteria that became highly resistant to other traditional antibiotics.
Gram-positive bacteria are called such because they give a positive result when put under the Gram stain test (38) .
How to Choose the Right CBD for Gastritis
A previously cited study showed the efficacy of THC or medical cannabis on gastritis symptoms, such as vomiting and nausea. However, as mentioned earlier, THC use is not legal in all US states.
Full-spectrum CBD oil contains all the Cannabis sativa plant components, including terpenes, flavonoids, fatty acids, essential oils, and trace amounts of THC.
It is suggested that full-spectrum oils provide full therapeutic benefits because of the synergy of all the active ingredients of the cannabis plant. This mechanism is called the entourage effect.
The THC content of full-spectrum CBD products (less than 0.30%) is allowed by federal laws. However, this minimal amount may still be detected by drug tests.
Individuals who want to purchase CBD products free of THC may buy broad-spectrum CBD. This type of CBD oil has all the ingredients of the full-spectrum oil except for THC.
For pure, isolated cannabidiol, CBD isolates may be purchased.
Full-spectrum CBD oils are recommended for gastritis treatment. Still, individuals are encouraged to speak to a medical professional before purchasing any CBD product.
It is also essential to research if a manufacturer or dispensary is credible and authorized by the government to sell CBD to avoid buying illegitimate products.
CBD Dosage for Gastritis
Currently, no standard dosage chart has been developed for CBD in treating gastritis. However, it is recommended to begin with a small amount of CBD .
If no adverse effects are seen, the dosage may be increased gradually until the desired effect is achieved.
Individuals using CBD for gastritis are encouraged to keep a journal of their reactions to the substance. They may refer to this journal during consultations with their physician.
Before adding CBD to one’s gastritis medication regimen, it is recommended to inform a medical professional first.
How to Take CBD for Gastritis
There are several options when taking CBD for gastritis.
Some formats, such as CBD oils and tinctures (drops), allow individuals to take CBD directly. Tinctures may be applied sublingually, or under the tongue, for added efficacy.
CBD oils may be mixed with food or beverages to mask CBD’s naturally grassy taste.
CBD pills, gelcaps, capsules, edibles, and gummies may be ingested. This format also allows people with gastritis to conveniently bring their CBD medication with them anywhere.
This format is also appropriate for people with gastritis problems who want to take a consistent dosage of CBD.
CBD topicals, such as balms, salves, lotions, and ointments, may also be used. During episodes of abdominal pain or upset stomach , these topicals may be massaged into the affected area.
Some topicals contain soothing ingredients, such as peppermint and menthol, for added pain relief.
For instantaneous effects, CBD may be inhaled via vape pens. However, vaping CBD may be challenging, as it is hard to determine how much CBD was already taken.
In some individuals, vaping may also cause lung problems (39) .
According to Johns Hopkins Medicine, gastritis occurs when the stomach lining gets swollen (40) .
Gastritis may be caused by drinking excessive amounts of alcohol, eating spicy food , extreme stress, smoking, and long-term use of pain and fever medications.
Bacterial infections , major surgeries, and traumatic injuries or burns may also cause gastritis.
Gastritis may be classified as acute gastritis or chronic gastritis . Gastritis symptoms include the following (41) :
- Stomach upset or pain
- Belching and hiccups
- Bloating or gas
- Bleeding of the belly or abdomen
- Loss of appetite
- Nausea and vomiting
- Blood in the vomit or stool
- Weight loss
When untreated, gastritis may also result in other more severe health complications. These conditions include peptic ulcer disease (painful sores in the upper digestive tract) and tumors that could lead to stomach cancer .
A study also found that gastritis was associated with an increased prevalence of panic attacks, social phobia, major depression, and mood disorders (42) .
Previously mentioned studies found that CBD might be useful in treating gastritis symptoms, such as inflammation, nausea, and pain.
Compared with conventional medications prescribed for gastritis, CBD is generally safe because of its minimal side effects.
Like honey, CBD was found to have antibacterial properties.
CBD also comes in different forms and formulations, giving individuals with gastritis several options.
While CBD has been deemed for its favorable safety profile, in some individuals, CBD oil may be hard on the stomach.
For a more efficient treatment, it is best to consult with a healthcare provider before taking any CBD product for gastritis.
Does CBD Work for Gastritis? Research in 2020 revealed that cannabidiol (CBD) had anti-inflammatory effects in rodent models of intestinal inflammation. Gastritis is an inflammation of the stomach lining.
Gastritis & CBD
Medical content reviewed by Dr. Joseph Rosado, MD, M.B.A, Chief Medical Officer
Patients with gastritis have a new alternative to conventional treatments: cannabidiol (CBD). Find out how this compound can relieve inflammation and other gastritis symptoms.
What Is Gastritis?
Gastritis happens when your stomach lining becomes swollen or inflamed. You can have an acute case of the condition that goes away after a short time. However, in cases of chronic gastritis, the swelling happens over time or reoccurs.
The primary symptom of gastritis, inflammation, causes the condition’s secondary symptoms. People with gastritis can feel pain and have an upset stomach. Gastritis symptoms also include indigestion, appetite loss, heartburn, vomiting, dark stools and hiccups. The stress of having chronic gastritis increases the patient’s chance of developing mental health symptoms.
Chronic gastritis can lead to severe complications when left untreated. It can raise your risk of stomach cancer or make you feel full early. A form of gastritis called erosive gastritis also wears your stomach lining away. This damage creates painful ulcers and erosions. A doctor can resolve these issues and help you manage your condition.
Gastritis and Your Endocannabinoid System
Everyone has an endocannabinoid system (ECS) that uses and creates cannabinoids. Cannabinoids, the substances found in marijuana and the body, regulate your everyday functions. Your ECS includes endocannabinoids, the cannabinoids made by your body, and the CB1 and CB2 receptors. The CB1 and CB2 receptors bind to cannabinoids and send signals to the connected tissue and nerves. Many of the functions regulated by the ECS have a connection to your stomach and gastritis.
The vagus nerve that connects your gut and brain has cannabinoid receptors that manage their communication. Your vagus nerve’s cannabinoid receptors regulate how the vagus nerve transmits signals between your brain and gut. When you use cannabis medicine, the receptors use the cannabinoids to send benefits to your digestive system.
Your body also produces cannabinoids to regulate its immune response. When the source of your gastritis irritates your stomach, the lining’s immune cells trigger inflammation. The cannabinoid receptors in the lining also release anandamide, an endocannabinoid created by your body. Anandamide maintains your pain signals and immune cells to control your body’s response to tissue damage. By increasing the anandamide in your body, you can regulate pain and inflammation.
Treating Gastritis Symptoms With CBD
CBD has a unique interaction with your ECS compared to other cannabinoids. While most cannabinoids attach to receptors, CBD enhances your ECS’ ability to do its job. It works with various parts of the ECS to boost your body’s functions.
By improving your tissue’s ability to retain anandamide, CBD helps it control pain and inflammation. CBD blocks FAAH, a fatty acid that breaks anandamide down. With FAAH’s effects reduced, your body can keep higher amounts of anandamide and let it do its job for a longer time. As a result, you have less inflammation and reduced feelings of pain.
You may also be able to use CBD to control nausea caused by gastritis. Certain cannabinoids seem to reduce feelings of nausea, although we don’t know the exact way it works. We do understand that THC has a role to play in nausea relief, so medicine that contains the compound will also help.
If you have emotional symptoms like depression or anxiety, increased anandamide levels can improve your mood. Some patients with chronic gastritis develop mood disorders because of the stress associated with having the condition. Anandamide promotes feelings of relaxation and happiness to treat these symptoms.
Addressing Some of Gastritis’ Causes With CBD
Taking CBD also provides indirect benefits for gastritis by letting you avoid its causes. If you have gastritis due to chronic nausea or painkillers, CBD can help. Its nausea-relieving properties reduce the frequency of vomiting to keep your stomach lining intact. You may also have the opportunity to use it to relieve pain and lower your painkiller dose.
How to Choose the Right CBD Medication for Gastritis
You can buy CBD products in a variety of forms that have their strengths and weaknesses. Most patients in the United States can buy CBD oil because of its ambiguous legal status. CBD oil can relieve symptoms if it has a sufficient amount of CBD, so make sure your medicine has a high enough concentration. Patients can also get CBD medicine from a dispensary as an adult over 21 or medical marijuana patient.
When you ingest CBD medicine as a pill, edible or oil, more medication will reach your stomach compared to other methods. However, everyone has different symptoms and circumstances. We recommend getting advice from a cannabis-trained doctor for the best results.
More Resources From MarijuanaDoctors.com
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