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coli 41949 pathogen obtained from a human clinical isolate was infused via the jugular vein into female Yorkshire Swine, 30–50 kg ( n = 2 for each time point). Animals were randomly assigned and no blinding was performed. Animals received an initial dose of bacteria (0·5 × 10 7 CFU/kg) at the start of the experiment ( T = 0 h) followed by a 6 h infusion of 5·0 × 10 7 CFU/kg ( T = 3 to 9 h).

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