best cbd oil for crohn’s disease

Best CBD Oil for Crohn’s Disease – November 2020

Can CBD oil help with Crohn’s disease?

  • Crohn’s disease is a prevalent inflammation of the digestive tract that is often recognized by symptoms of abdominal pain, severe diarrhea, malnutrition, fatigue, and weight loss. It is a common type of inflammatory bowel disease (IBD), affecting more than 3 million Americans in 2015 (1 ) .
  • Despite having no cure, doctors have developed therapies that may alleviate the symptoms of Crohn’s disease, allowing patients to function normally (2 ) .
  • One particularly promising treatment is CBD (cannabidiol), a compound from the Cannabis sativa plant that supposedly has several therapeutic applications (3 ) .
  • Several studies have shown that CBD can inhibit intestinal inflammation, provide pain relief, and improve the overall quality of life for patients with IBD (4-6 ) .
  • As with any medication, it is in the best interest of people to consult a doctor before incorporating CBD into their regimen.

Best CBD Oil for Crohn’s Disease

Spruce 750mg Lab Grade CBD Oil

Specifically formulated to be more palatable to CBD users
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Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

  • &nbsp Mid-strength
  • &nbsp Natural peppermint flavor
  • &nbsp Made from 100% organic and natural ingredients
  • &nbsp No other flavors
Discount pricing available? 20% Off Coupon Code: CBDCLINICALS

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil

Perfect for anyone who are looking for CBD products that promote a healthy body and mind.
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Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

  • &nbsp Pure CBD hemp
  • &nbsp All natural
  • &nbsp Approximately 300 drops total
  • &nbsp No other flavors
Discount pricing available? 20% Off Coupon Code: CBDCLINICALS20

Sabaidee Super Good Vibes CBD Oil

4x the strength of a regular cbd oil
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Super Good Vibes CBD Oil provides the purest and highest quality Cannabidiol (CBD) on the market as well as other high quality phytocannabinoids, terpenes, vitamins, omega fatty acids, trace minerals, and other beneficial for your health elements, which all work together to provide benefits.

  • &nbsp Extra strong
  • &nbsp Significant benefits with just a few drops
  • &nbsp 100% Natural ingredients
  • &nbsp No other flavors
Discount pricing available? 15% Off Coupon Code: CBDCLINICALS15

cbdMD CBD Oil Tincture Natural 1500mg

Uses USA hemp that is grown on non-GMO farms, and is both vegan and gluten-free
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cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

  • &nbsp Various delicious flavors to choose from
  • &nbsp Has vegan, organic, and gluten-free ingredients
  • &nbsp Free shipping for this particular product within USA
  • &nbsp World-class customer service team
  • &nbsp cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Discount pricing available? 15% Off Coupon Code: cbdMD15

Why Some People Are Turning to CBD for Crohn’s Disease

Crohn’s disease is an inflammation of the digestive tract characterized by severe diarrhea, abdominal pain, weight loss, malnutrition, and fatigue. It is one of the most common types of inflammatory bowel disease (IBD) that affects more than 3 million American adults in 2015 (7 ) .

The disease is often associated with a decreased quality of life and frequent complications that require hospitalization and, sometimes, surgical procedures. Although Crohn’s disease has no cure, there are several therapies available that may reduce its symptoms and allow patients to function well (8 ) .

CBD, also known as cannabidiol, may be a promising solution for people with an IBD , such as Crohn’s disease. CBD is one of the primary compounds of the cannabis plant that, according to research, has several therapeutic applications (9 ) .

Researchers of a study in 2011 found that CBD might inhibit inflammation in the intestine of mice with ulcerative colitis, another common IBD. They also learned that the compound reduced intestinal damage by counteracting the inflammatory environment caused by the disease (10 ) .

Another study on rats with colitis has shown that CBD, together with THC (tetrahydrocannabinol), was able to reduce inflammatory markers in the subjects (11 ) . THC is also another chemical compound obtained from cannabi s (medical marijuana). THC is often used together with CBD for medical conditions.

The study further showed that this combination of compounds lowered the occurrence of colitis symptoms . Scientists learned that CBD enhanced THC’s effects in alleviating the inflammatory bowel disease in rodents (12 ) .

A study in 2012 showed that applying CBD topically to mice with colitis led to significant improvement in the subjects’ health conditions (13 ) . Meanwhile, rodents in another trial were given CBD orally to treat colitis, resulting in the reduction of injury and bowel movement commonly linked to IBD (14 ) .

The studies mentioned were performed on animals. Further research would be necessary to see if the same outcomes can be obtained from studies conducted in human subjects.

Additionally, CBD is reported to engage with a re ceptor kn own as GPR55, which plays a vital role in intestinal inflammation (15 ) .

Scientists believe that the endocannabinoid system (ECS), which is in charge of numerous body functions, is a potential therapeutic target for treating IBD. They also think that its compatibility with cannabinoids , like CBD , is how these compounds bring about their therapeutic effects.

How CBD Oil Works to Help with Crohn’s Disease

The ECS assumes a crucial role in controlling many fundamental functions of the body. It also affects the gastrointestinal tract (GI tract) by managing gut homeostasis and movement (16 ) .

In people with Crohn’s disease, the ailment interrupts the ECS receptors designed to ensure efficient gastrointestinal operations. These chemical structures are expected to protect the gut by preventing the formation of inflammation and reducing intestinal motility.

One of the main goals of the ECS is to promote balance in the body, primarily through its CB1 and CB2 receptors. CBD, being a cannabinoid that is compatible with these structures, may help in accomplishing this objective.

Scientists believe that dosing with CBD can stimulate the cannabinoid receptors in charge of anti-inflammatory effects (17 ) . By activating these chemicals, cannabis products , like CBD oi l , may inhibit inflammation and provide pain symptom relief.

This reduction in inflammation should contribute to regulating gut pain and irritation while normalizing bowel movement – all of which are clinical signs associated with Crohn’s disease.

The Pros and Cons of CBD Oil for Crohn’s Disease

The Pros
  • Cannabinoids , like CBD , interact with the ECS to bring about their purported therapeutic benefits, one of which is providing balance in the digestive tract .
  • CBD has anti-inflammatory properties, which scientists believe can reduce the common symptoms of IBD.
  • According to a study, cannabinoids, such as CBD, may alleviate abdominal pain and diarrhea, two common symptoms of Crohn’s disease (18 ) .
  • CBD is a natural compound acquired from the cannabis plant. It does not have mind-altering effects, unlike THC.
  • The United States Food and Drug Administration encourages and supports scientifically-based research on CBD (19 ) .
The Cons
  • There is a distinct lack of human clinical trials on CBD for Crohn’s disease, as most of the studies were conducted on rodents.
  • Some of the animal studies show inconclusive results on CBD’s efficacy for IBD.
  • The FDA does not approve a marketing application on cannabis products for treating any disease or health condition (20 ) .
  • Epidiolex is the only CBD product that the FDA allows . It is a prescribed drug for treating two rare forms of epilepsy (21 ) .

How CBD Oil Compares to Alternative Treatments for Crohn’s Disease

Herbal treatments , like aloe vera juice, chamomile, and peppermint , are said to ease the symptoms associated with IBD. Meanwhile, probiotics may help in increasing the naturally good bacteria in the gut and restore balance (22 ) .

Naturopathic therapies involving dietary changes are also said to successfully manage IBD, including Crohn’s symptoms (23 ) .

Meanwhile, studies on CBD have shown that the compound contains properties that might help in alleviating chronic pain and fighting inflammation.

Today, CBD products are mixed with aloe vera, chamomile, peppermint, and other herbs to bring about the maximum effect in counteracting the symptoms of Crohn’s disease activity. CBD infused with probiotics are also popular in helping maintain a healthy intestinal tract.

How to Choose the Best CBD Oil for Crohn’s Disease

There are three main types of CBD products that people can consider in easing IBD and Crohn’s disease symptoms.

Full-spectrum CBD contains all of the chemicals present in cannabis , including varying amounts of THC. These usually are sold as CBD tinctures, vaping oils, creams, and edibles.

According to federal law, this type of CBD is only allowed to have a maximum of 0.3% THC content.

Meanwhile, broad-spectrum CBD also has the compounds of cannabis except for THC. The psychoactive compound is removed to cater to individuals who do not wish to consume it together with their CBD.

Finally, there are CBD isolates that are made of pure cannabidiol. These are often obtained from hemp plants and do not contain the other compounds of medical cannabis .

Users should seek medical advice from a doctor before deciding to use CBD for Crohn’s disease.

Here are several tips to help choose the safest and most reliable form of CBD today:

  1. Buy high-quality CBD products only and find legitimate brands that sell them. Most reputable companies grow their hemp or purchase them from reliable producers.
  2. Read up on product reviews before buying from an online shop. If they are a physical store or dispensary, check whether the store is allowed by the government to sell.
  3. Compare company claims with third-party lab reports by obtaining a certificate of analysis (COA) for each CBD product purchased.
  4. Be aware of the precise legal stipulations associated with CBD use in the area where one is going to buy and consume the extract.
  5. Look for certification codes for CBD products. There are certification authorities that approve only certain CBD goods after they have undergone thorough screening tests.

CBD Dosage for Crohn’s Disease

Since CBD is a relatively new medical treatment of Crohn’s disease, healthcare providers are still figuring out the right dosage that is both effective and safe for users. It may be helpful to look at the dosage used in past clinical trials to get the proper amount.

One small study concerning CBD for treating ulcerative colitis had its participants take 50 mg of CBD oil twice each day, increasing the dose to as much as 250 mg. Researchers found that users that took CBD had significant clinical remission and improved quality of life (24 ) .

Additionally, the study revealed that the participants did not experience severe side effects after ten weeks of treatment with cannabis use.

Meanwhile, other health experts recommend a starting dose of 40 mg and gradually increase the amount from there.

Like with any medication, the best advice would be to start at the lowest effective dose and gradually increase this as needed. Keep in mind that lower doses often have lower side effects compared to higher ones with increased risk.

How to Take CBD Oil for Crohn’s Disease

CBD products are available in various delivery formats. The following are the forms of CBD that can potentially relieve the symptoms of Crohn’s disease:

  • CBD capsules and pills – Studies done on using CBD capsules for IBD have shown improved quality of life in the human subjects consuming the product daily.
  • CBD edibles – These CBD products may be found as gummies or chocolates. They are ideal for users that have trouble swallowing capsules.
  • CBD oils and tinctures – These are often applied under the tongue and are known to take effect immediately.


Crohn’s disease is an inflammatory bowel disease that is known to affect more than 3 million Americans. This health condition is often linked to a poor quality of life for its patients and regular complications that lead to hospitalization and surgery.

The symptoms that are associated with the disease include abdominal pain, severe diarrhea, malnutrition, weight loss, and fatigue.

Although there is no cure for Crohn’s disease, there are several forms of therapy that could help reduce symptoms and allow IBD patients to function normally. CBD is one promising solution that, according to research, can alleviate the pain and gut inflammation associated with Crohn’s disease.

However, most of the studies that were made for the disease were carried out on animals. No direct evidence exists that proves CBD as an effective treatment for IBD and Crohn’s disease.

Interested users should seek advice from a medical professional before deciding to incorporate CBD into their diet.

Can CBD oil help with Crohn's disease, and if so, how? Crohn's disease is a prevalent inflammation of the digestive tract that is often recognized by symptoms of abdominal pain, severe diarrhea, malnutrition, fatigue, and weight loss.

Top 10 Best CBD Oils for Crohn’s Disease

This article will cover the top 10 CBD oils for potentially helping those with Crohn’s Disease.

Crohn’s Disease, a type of inflammatory bowel disease, is a lifelong condition in which sections of the digestive system become painfully inflamed. The cause of Crohn’s Disease is currently unknown, although it is thought to be a result of genetic makeup or an issue with the immune system. Although the disease is not life-threatening, many people with Crohn’s Disease find it difficult to live healthy lives as symptoms and flare-ups frequently interrupt daily activities. These symptoms can include bloody stool, diarrhea, cramps, weight loss, or fatigue. Flare-ups can come at any time for Crohn’s patients, and it is nearly impossible to control the symptoms when they become present.

There is currently no cure for Crohn’s Disease, but there are a few treatments that can help manage it. Although mainstream medical research on CBD for Crohn’s is limited, many people have stated it helps them manage their symptoms. CBD has been frequently studied as an anti-inflammatory agent in the body, which is one of the leading symptoms of Crohn’s Disease. In this article, we will be discussing the top 10 CBD oils for Crohn’s Disease, so keep reading if you want our favorite recommendations.

1. 4 Corners Cannabis

Brothers Brian and Justin Jasiewicz started 4 Corners Cannabis out of a garage, a tiny kitchen, and a neighbor’s field in 2013. Today, it’s a well-known brand in the CBD world. The company is a true seed to shelf operation, tending and harvesting their own hemp, and extracting their CBD by using pure organic cane sugar alcohol, which they claim keeps the plant’s genetics intact.

Their Earthy Avocado Oral Tincture is made with full-spectrum CBD and virgin organic avocado oil. It’s ideal for those with allergies to citrus or coconut. Choose from potencies ranging from 250 to 2000 mg of CBD per bottle. It comes with a graduated dropper for easy measuring.

2. Hemplucid

Hemplucid is on a mission to produce pure products that help people “experience life again”. They put a high priority on transparency (hence the name) and quality, providing some of the best CBD products you can find online. They have been selectively breeding hemp for over a decade, a practice they believe has produced genetically superior plants.

The brand’s Full-Spectrum CBD Tincture can be purchased with a hemp seed oil or and MCT oil carrier. Customers can choose from potencies as low as 250 mg to as high as 2000 mg of CBD in each dropper bottle. There are no artificial colors or flavorings, and they have a decidedly “hempy” taste. However, if you are looking for a pure CBD oil containing the whole range of cannabinoids and terpenes found in the plant, Hemplucid is an ideal choice.

3. Infinite CBD

Based out of Colorado, Infinite CBD is a company that does not use typical full-spectrum CBD oils, instead using only CBD isolate. Although you won’t have the benefit of the entourage effect with these products, CBD isolate contains no THC, so its ideal for those concerned about the addition of this cannabinoid.

The CBD isolate droppers from Infinite can be purchased in concentrations ranging from 250 to 5000 mg of CBD in each bottle. The company uses coconut oil as a carrier oil for easy digestion and high bioavailability. They recommend taking the oil sublingually and letting it absorb for up to a minute. It can also be used topically by massaging it into the skin.

4. Elixinol

Elixinol is a brand offering some of the best CBD tinctures on the market. They’ve been working with hemp for over 25 years, and claim to have the most knowledgeable team of growers, extractors, formulators, and processors in the industry. Their CBD is CO2 extracted and sourced from US-grown hemp. It contains no chemicals or synthetic ingredients.

The brand offers several CBD formations, including full-spectrum, broad-spectrum, and organic oils. Their Daily Balance Liposome tincture stands out, however, due to the advanced technology used to produce it. By encapsulating CBD and MCT coconut oil in a phospholipid solution, they’ve created a product that is both fat and water-soluble. This process makes the CBD highly bioavailable to the cells.


CBDMD is a leading brand in the hemp industry, with years of solid ratings and a great safety profile. They offer an array of CBD products including gummies, tinctures, pet products, capsules, topicals, and more. Their products are made with broad-spectrum CBD. This ensures that they retain all of the beneficial terpenes and cannabinoids present in whole-plant formulations, but without any THC.

The 1000 mg broad-spectrum tincture is an inexpensive CBD oil available in natural, berry, orange, or mint flavor. It has been third-party lab tested in an ISO certified facility, and the results of that analysis can be viewed right on the product page. The company cautions that it may take two to three weeks of regular use to see results as it takes time for CBD to build up in the body.

6. Green Gorilla

Green Gorilla has created a line of proprietary CBD products that are unique from anything else on the market. This line is their Hemp & Olive line, which combines whole plant CBD with organic olive oil. This combination increases bioavailability and CBD’s impact on the body, as extra virgin olive oil already has many synergistic positive effects.

This full-spectrum oil is sourced from organically-grown hemp and can be purchased in potencies of 1200,2400, or 3000 mg of CBD per bottle. Unlike most brands that offer CBD in a dropper bottle, Green Gorilla utilizes a spray, which may be easier for some users. They recommend starting with five pumps a day. The brand uses only the aerial parts of the hemp plant to ensure all possible terpenes and flavonoids remain intact in the final formulation.

7. Fab

Fab CBD is quickly becoming an industry leader with its array of popular products. The company uses only organically grown Colorado hemp for their CBD, and it is both CO2- extracted and third-party lab tested for quality assurance.

Their CBD oil drops come in citrus, mint, vanilla, natural, or berry in your choice of potencies ranging from 300 to 2400 milligrams. They are non-GMO and made to order so you know you are getting a fresh product—not something that has been on the shelf for a while. The oil will keep for up to 12 months stored in a cool, dark place.

8. Endoca

For those new to CBD, this 300 mg CBD oil from Endoca is an ideal option. For starters, it is an inexpensive way to get started. But accurately measuring dosage to see how CBD oil affects you is another important factor for many. Endoca makes that an easy task. Each drop of oil contains one milligram of CBD, so adjusting the optimum dose for your needs is simple.

This is a true full-spectrum product, with all of the additional cannabinoids and terpenes intact. It’s sourced from organically-grown hemp and is GMP-certified. Endoca controls the entire process from seed to shelf, testing each product through an independent laboratory. The brand has been recognized by the UN for its sustainable practices.

9. NuLeaf Naturals

Founded in 2014 by plant medicine-focused entrepreneurs, NuLeaf Naturals is a company which is committed to crafting their products with care and ensuring the highest possible quality. They derive all of their hemp from Colorado and it has been grown using only sustainable and organic farming practices. Third-party lab results are readily available on the site.

Their full-spectrum hemp oil tincture can be purchased in strengths ranging from 300 to 6000 mg, contains perfect no matter what potency you are looking for. The taste is rich and earthy. One drop is equivalent to 3mg of CBD, which makes it super-easy to calculate an accurate serving size. They recommend holding a dose of your discretion under the tongue for 30 seconds before swallowing to experience the full effects.

10. Lazarus Naturals

Lazarus Naturals was founded with the idea that everyone should have access to quality CBD products, regardless of their financial restrictions. Not only does the company make their products very affordable, but they also offer a 60% discount to veterans, those on disability, or those in low-income households.

Their high potency CBD isolate contains 3000mg of pure CBD in a two-ounce container, which is perfect if you’re looking for a CBD product that will last you a bit longer. Although you won’t get the added benefit of the entourage effect, you can be assured that this product is pure and contains no THC. The company recommends taking 1ml as needed and waiting up to two hours for the product to take full effect.

Research on CBD and Crohn’s Disease

Among mainstream medical studies, CBD and Crohn’s Disease have had mixed results. In some situations, CBD has helped significantly in the treatment of Crohn’s Disease as well as with the patient’s general quality of life. However, other studies have presented findings that did not align with this idea. The consensus is that, although more research certainly needs to be done, CBD likely does help some people in the treatment of their Crohn’s Disease symptoms.

In a double-blind study conducted by Tel Aviv University in Israel, participants were given either a CBD treatment or a placebo, starting with 15mg a day and increasing according to the person’s reaction. On average, participants in the experimental group were taking 222 mg of CBD a day, as well as some THC.

The experimental group showed a significant improvement in both their symptoms and quality of life, but it was found that the inflammatory markers did not significantly improve. The takeaway from this kind of result is that while CBD could help people to achieve symptomatic relief, it should not currently replace a traditional form of treatment. However, this is not worthless information. Despite not being able to replace conventional therapeutic methods, CBD could certainly become a valuable addition.

In a 2018 study done by the University of Western Ontario in Canada, 93 participants were given whole-plant cannabis to test the effects of the compounds on Crohn’s Disease. The study was done over eight weeks, and the experimental group had some particularly interesting results. 45 percent of the group taking the cannabis went into full clinical remission when only 10 percent of the group taking the placebo did.

Additionally, 91 percent of the cannabis group had some significant medical response to cannabis, while only 40 percent of the placebo group had a response. While these findings are not exactly clear in their results, they do suggest that perhaps the relationship between cannabis and Crohn’s Disease could be significant.

In another 2018 study conducted by the University of Massachusetts and the University of Bath, England, it was suggested that cannabinoids could be used to prevent inflammation and maintain homeostasis. Since these are functions that the endocannabinoid system already carries out, this idea is not so far-fetched.

The study even suggested that cannabinoids could essentially “turn off” inflammation from irritable bowel disease. Throughout researching, scientists discovered that endocannabinoids travel along the lining of the gut and that these endocannabinoids are similar to the ones in cannabis.

Cannabinoids and Crohn’s Disease

It is hypothesized that when the human body does not have enough of these endocannabinoids, this is when gut inflammation can become irregular and result in painful symptoms. This hypothesis could explain why, when taking CBD, these cannabinoid levels improve symptoms.

CBD has a definite positive impact at least on Crohn’s Disease—at least anecdotally—as people continue to use it in their daily battle with their symptoms. This widespread use is likely because CBD works for many people with severe Crohn’s Disease, despite mainstream medicine not yet being able to prove it.

A great thing to consider when thinking about trying CBD for your Crohn’s Disease is that whether it works or not, you likely won’t suffer any ill effects. CBD has been proven to be non-addictive and has not shown to have any significant adverse side effects. It can also be stopped and started at any time without issues.

If you are suffering and can’t seem to find the answers, talk to your doctor about trying CBD for your symptoms.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

All content at Best Choice Reviews concerning CBD (Cannabidiol) or other health-related matters are for informational purposes only and are not to be considered as a substitute for medical advice, diagnosis, or treatment. If a reader has further questions about the use of these products, we encourage them to consult with a licensed physician or other qualified health care provider. The information included here is for educational purposes only and Best Choice Reviews is not responsible for inappropriate use of these products.

Top 10 Best CBD Oils for Crohn’s Disease This article will cover the top 10 CBD oils for potentially helping those with Crohn’s Disease. Crohn’s Disease, a type of inflammatory bowel disease,